INT175557

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Context Info
Confidence 0.55
First Reported 2003
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.73
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (CASR) signal transducer activity (CASR)
CASR (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 39 70.72 Quite High
Pain 16 50.00 Quite Low
agonist 1 19.80 Low Low
Lasting pain 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Morphine 1 5.00 Very Low Very Low Very Low
analgesia 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypercalcemia 39 99.60 Very High Very High Very High
Pancreatitis 69 98.20 Very High Very High Very High
Osteoporosis 3 86.36 High High
Disease 15 77.76 Quite High
Fasciculation 4 66.76 Quite High
Pain 17 50.00 Quite Low
Breast Cancer 1 41.60 Quite Low
Congenital Anomalies 2 8.72 Low Low
Disorders Of Creatine Metabolism 2 5.08 Very Low Very Low Very Low
Fever 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is possible that a specific pattern of CaSR expression in our patient has been responsible for the described findings.
Spec (possible) Negative_regulation (pattern) of Gene_expression (expression) of CaSR
1) Confidence 0.55 Published 2010 Journal J Med Case Reports Section Body Doc Link PMC2907400 Disease Relevance 0.23 Pain Relevance 0
While a heterozygous inactivating CASR mutation leads to FHH, homozygous mutations result in severe neonatal pHPT.
Negative_regulation (inactivating) of Gene_expression (mutation) of CASR associated with hypercalcemia
2) Confidence 0.43 Published 2003 Journal BMC Gastroenterol Section Body Doc Link PMC317302 Disease Relevance 1.50 Pain Relevance 0.07

General Comments

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