INT17560

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Context Info
Confidence 0.08
First Reported 1991
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.49
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Scn7a)
Scn7a (Mus musculus)
Pain Link Frequency Relevance Heat
tetrodotoxin 1 99.98 Very High Very High Very High
antagonist 1 96.52 Very High Very High Very High
Calcium channel 1 90.28 High High
Action potential 177 88.84 High High
unmyelinated 8 5.00 Very Low Very Low Very Low
Pyramidal cell 6 5.00 Very Low Very Low Very Low
Axonal channel 4 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
local anesthetic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 3 98.12 Very High Very High Very High
Giardiasis 2 75.00 Quite High
Diarrhoea 1 75.00 Quite High
Pain 2 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Male Infertility 2 5.00 Very Low Very Low Very Low
Gastroenteritis 1 5.00 Very Low Very Low Very Low
Aging 1 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 1 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The addition of the neurotoxin, tetrodotoxin caused net absorption of Na+, Cl- and net secretion of Ca2+ in the control group, but it could not produce any effect on the fluxes of these ions in the infected group.
Positive_regulation (caused) of Localization (secretion) of Na associated with tetrodotoxin
1) Confidence 0.08 Published 1991 Journal J Diarrhoeal Dis Res Section Abstract Doc Link 1918833 Disease Relevance 0.49 Pain Relevance 0.19
As K channels are predominantly closed, the net membrane and axial current variability must result from Na channel noise (cf. matching SD curves between ?
Positive_regulation (result) of Localization (noise) of Na
2) Confidence 0.03 Published 2007 Journal PLoS Computational Biology Section Body Doc Link PMC1864994 Disease Relevance 0 Pain Relevance 0.08
The RSBFI increased in response to the Na+ entry that occurred upon addition of monensin to cells in medium HS (Fig. 1B) and decreased when monensin promoted Na+ release into a Na+-deficient (NMDG-substituted) medium (Fig. 1C).
Positive_regulation (promoted) of Localization (release) of Na
3) Confidence 0.03 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2729922 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.

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