INT175798

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Context Info
Confidence 0.01
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 3.55
Pain Relevance 1.82

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Gorasp2)
Anatomy Link Frequency
lymphocytes 1
Gorasp2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 243 99.24 Very High Very High Very High
substance P 15 99.24 Very High Very High Very High
Neuropeptide 21 98.44 Very High Very High Very High
Morphine 12 73.36 Quite High
agonist 15 73.00 Quite High
Opioid 12 72.32 Quite High
Inflammation 201 69.56 Quite High
Osteoarthritis 3 65.68 Quite High
Peripheral nervous system 9 54.24 Quite High
antagonist 3 38.00 Quite Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 243 99.24 Very High Very High Very High
Disease 81 91.32 High High
Stress 39 90.24 High High
INFLAMMATION 213 69.56 Quite High
Osteoarthritis 3 65.68 Quite High
Hypoglycemia 9 33.24 Quite Low
Arthritis 54 32.96 Quite Low
Congenital Anomalies 6 22.16 Low Low
Sprains And Strains 15 5.00 Very Low Very Low Very Low
Autoimmune Disease 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In some cases, a decrease in the number of GRs has been shown in RA, or reduced glucocorticoid sensitivity has been observed due to GR?
Negative_regulation (decrease) of GRs associated with rheumatoid arthritis
1) Confidence 0.01 Published 2003 Journal Arthritis Res Ther Section Body Doc Link PMC333413 Disease Relevance 1.17 Pain Relevance 0.96
In one study, normal or even slightly elevated numbers of GRs in peripheral blood mononuclear cells (PBMCs) were seen in untreated patients with RA [236], whereas other studies have shown a decrease in the number of GR molecules in the lymphocytes of patients with RA in comparison with controls [237].
Negative_regulation (numbers) of GRs in lymphocytes associated with rheumatoid arthritis
2) Confidence 0.01 Published 2003 Journal Arthritis Res Ther Section Body Doc Link PMC333413 Disease Relevance 1.19 Pain Relevance 0.43
Quantification of the numbers of GRs by ligand binding studies has produced contrasting results.
Negative_regulation (numbers) of GRs
3) Confidence 0.01 Published 2003 Journal Arthritis Res Ther Section Body Doc Link PMC333413 Disease Relevance 1.19 Pain Relevance 0.42

General Comments

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