INT175888

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Context Info
Confidence 0.04
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.32
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (POLR2B) nucleolus (POLR2B) nucleus (POLR2B)
DNA binding (POLR2B) nucleotidyltransferase activity (POLR2B)
POLR2B (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 2 66.84 Quite High
agonist 4 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Helminth Infection 1 85.40 High High
Polycystic Kidney Disease 6 64.48 Quite High
Chronic Renal Failure 9 61.20 Quite High
Hypertension 2 54.00 Quite High
Colon Cancer 53 50.00 Quite Low
Disease 17 47.92 Quite Low
Autosomal Dominant Polycystic Kidney 21 44.60 Quite Low
Targeted Disruption 1 20.64 Low Low
Cervical Cancer 1 12.56 Low Low
Cancer 31 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Consistent with the MeDIP data, HDAC1 was tightly bound to PPARG promoter, whereas RNA-Polymerase II (RNAPol-II) and its phosphorylated form (P-RNAPol-II) were barely present in untreated HCT116 cells (Figure 3, panel A).
Gene_expression (present) of RNA-Polymerase II
1) Confidence 0.04 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2997072 Disease Relevance 0 Pain Relevance 0.03
The presence of L3287del mutation in five affected members (II-1, II-2, III-2, III-4, and III-6) but its absence in eight unaffected members of PK002 family were demonstrated (Figure 5D).


Gene_expression (members) of II-2
2) Confidence 0.00 Published 2004 Journal BMC Med Genet Section Body Doc Link PMC356914 Disease Relevance 0.32 Pain Relevance 0

General Comments

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