INT175896

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Context Info
Confidence 0.53
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.22
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (PKD1) nucleus (PKD1) cilium (PKD1)
cytoplasm (PKD1)
PKD1 (Homo sapiens)
Pain Link Frequency Relevance Heat
headache 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 32 93.92 High High
Cerebral Aneurysm 8 84.44 Quite High
Cyst 6 81.92 Quite High
Chronic Renal Failure 18 81.20 Quite High
Autosomal Dominant Polycystic Kidney 42 68.12 Quite High
Polycystic Kidney Disease 12 64.88 Quite High
Hypertension 4 5.00 Very Low Very Low Very Low
Helminth Infection 2 5.00 Very Low Very Low Very Low
Coronary Artery Disease 2 5.00 Very Low Very Low Very Low
Cervical Cancer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The analysis of PKD1 transcript provides an opportunity for ex vivo study of splicing defects prior to identification of causative mutations.
Transcription (transcript) of PKD1
1) Confidence 0.53 Published 2004 Journal BMC Med Genet Section Body Doc Link PMC356914 Disease Relevance 0.23 Pain Relevance 0
PKD1 gene spans >50 kb of genomic DNA, containing 46 exons and transcribing ~14-kb mRNA [3-6] that encodes a large membrane-associated glycoprotein, polycystin-1, comprising 4,302 amino acids.
Transcription (transcribing) of polycystin-1
2) Confidence 0.53 Published 2004 Journal BMC Med Genet Section Body Doc Link PMC356914 Disease Relevance 0.99 Pain Relevance 0

General Comments

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