INT175956

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Context Info
Confidence 0.49
First Reported 2004
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.94
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (RSF1) histone binding (RSF1) ATPase activity (RSF1)
nucleus (RSF1)
RSF1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 45 90.00 High High
methotrexate 10 24.80 Low Low
Neuropathic pain 1 9.00 Low Low
depression 1 8.28 Low Low
rheumatoid arthritis 38 5.00 Very Low Very Low Very Low
cINOD 4 5.00 Very Low Very Low Very Low
COX-2 inhibitor 2 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
Rheumatism 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 108 98.50 Very High Very High Very High
INFLAMMATION 49 90.00 High High
Death 10 81.12 Quite High
Cancer 94 51.04 Quite High
Necrosis 6 44.16 Quite Low
Neuropathic Pain 1 9.00 Low Low
Depression 1 8.28 Low Low
Injury 1 6.68 Low Low
Stress 2 6.24 Low Low
Rheumatoid Arthritis 38 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Among the 2 genes upregulated in ERBB2-amplified IBCs compared to ERBB2-amplified NIBCs, SQLE (8q24.13) was gained or amplified in IBCs but not in NIBCs while RSF1 (11q13.5) was not targeted by CNA in the two populations.
Neg (not) Gene_expression (targeted) of RSF1
1) Confidence 0.49 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2958950 Disease Relevance 0.30 Pain Relevance 0.13
activation was involved in the apoptotic effect of triptolide, we performed a luciferase reporter gene assay by co-transfection of RSF with a peroxisome proliferator response element (PPRE)-driven luciferase reporter plasmid and a PPAR?
Gene_expression (transfection) of RSF associated with apoptosis
2) Confidence 0.09 Published 2004 Journal BMC Pharmacol Section Body Doc Link PMC373449 Disease Relevance 0.56 Pain Relevance 0
RSF were plated in 96-well plastic plates (2 × 104 cells/well) and cultured for 24 h.
Gene_expression (plated) of RSF
3) Confidence 0.07 Published 2004 Journal BMC Pharmacol Section Body Doc Link PMC373449 Disease Relevance 0.08 Pain Relevance 0

General Comments

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