INT17597

Context Info Confidence 0.50 First Reported 1991 Last Reported 2006 Negated 0 Speculated 0 Reported most in Abstract Documents 3 Total Number 3 Disease Relevance 0 Pain Relevance 0.85

extracellular space (CFHR1) extracellular region (CFHR1)

Anatomy Link Frequency forelimb 2 CFHR1 (Homo sapiens)

Pain Link Frequency Relevance Heat Morphine 4 98.96 epidural 1 94.96 analgesia 1 94.24 narcan 7 89.28 Opioid 2 78.88 antagonist 1 65.36 cva 1 5.00 headache 1 5.00

Disease Link Frequency Relevance Heat Hemolytic Uremic Syndrome 14 50.00 Pressure And Volume Under Development 8 5.00 Disease 8 5.00 Renal Failure 5 5.00 Acute Renal Failure 4 5.00 Myocardial Infarction 3 5.00 Hypersensitivity 2 5.00 Recurrence 2 5.00 Thrombocytopenia 1 5.00 Age-related Macular Degeneration 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

If recombination occurred after the terminal exons of CFH and CFHL1 deletion of CFHL1 and CFHL3 would result.

Positive_regulation (result) of Gene_expression (deletion) of CFHL1

1) Confidence 0.50 Published 2006 Journal PLoS Medicine Section Body Doc Link PMC1626556 Disease Relevance 0 Pain Relevance 0

Morphine administration significantly decreased FHR, but it increased FHR variation and forelimb movements (LM).

Positive_regulation (increased) of Gene_expression (variation) of FHR in forelimb associated with morphine

2) Confidence 0.48 Published 2001 Journal J. Appl. Physiol. Section Abstract Doc Link 11247963 Disease Relevance 0 Pain Relevance 0.71

In this preliminary study, conventional attributes of the FHR, alone or in combination, did not predict metabolic acidemia.

Positive_regulation (attributes) of Gene_expression (attributes) of FHR

3) Confidence 0.41 Published 1991 Journal Obstet Gynecol Section Abstract Doc Link 1923162 Disease Relevance 0 Pain Relevance 0.14

General Comments

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