INT176185

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Context Info
Confidence 0.31
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.56
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (Hmgcr) embryo development (Hmgcr)
Hmgcr (Mus musculus)
Pain Link Frequency Relevance Heat
Bile 43 5.00 Very Low Very Low Very Low
agonist 6 5.00 Very Low Very Low Very Low
tolerance 5 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
dexamethasone 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 42 97.56 Very High Very High Very High
Disorder Of Lipid Metabolism 20 85.08 High High
Atherosclerosis 27 67.32 Quite High
Sprains And Strains 14 58.04 Quite High
Pressure And Volume Under Development 29 50.00 Quite Low
Body Weight 13 44.80 Quite Low
Metabolic Syndrome 18 38.32 Quite Low
Obesity 5 34.56 Quite Low
Disease 10 5.00 Very Low Very Low Very Low
Stress 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Expression of HMG-CoA reductase mRNA was decreased by ~50% and ~80% in the heterozygote and knockout mice respectively, in keeping with limited observations in human patients with this disorder [7].
Transcription (Expression) of HMG-CoA reductase associated with targeted disruption
1) Confidence 0.31 Published 2004 Journal BMC Med Section Body Doc Link PMC394351 Disease Relevance 0.30 Pain Relevance 0
HMG-CoA reductase mRNA abundance showed a significant interaction between the maternal diet and OB diet effect meaning that the effect of OB feeding was different according to maternal diet (P?
Transcription (abundance) of HMG-CoA reductase
2) Confidence 0.12 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2936567 Disease Relevance 0.26 Pain Relevance 0

General Comments

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