INT176244

Context Info Confidence 0.02 First Reported 2004 Last Reported 2004 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.31 Pain Relevance 0

nucleus (Pcna) intracellular (Pcna) DNA binding (Pcna) transcription factor binding (Pcna) cytoplasm (Pcna)

Pcna (Mus musculus)

Pain Link Frequency Relevance Heat cerebral cortex 9 5.00 metalloproteinase 4 5.00 antagonist 3 5.00 ischemia 2 5.00 Pain 1 5.00 alcohol 1 5.00 Multiple sclerosis 1 5.00 Hippocampus 1 5.00

Disease Link Frequency Relevance Heat Apoptosis 74 94.84 Repression 2 54.52 Suicidal Behaviour 27 50.00 Death 17 5.00 Neurodegenerative Disease 8 5.00 Adhesions 4 5.00 Cancer 4 5.00 Disease 2 5.00 Demyelinating Disease 1 5.00 Cv General 4 Under Development 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

We were particularly interested in the regulation of dual-purpose proteins like cyclin-A, p21/waf-1 and PCNA that not only regulate progression through cell cycle, but also participate in DNA repair and blockage of apoptosis.

Regulation (regulation) of cyclin associated with apoptosis

1) Confidence 0.02 Published 2004 Journal BMC Neurosci Section Body Doc Link PMC395829 Disease Relevance 0.31 Pain Relevance 0

General Comments

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