INT176253

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Context Info
Confidence 0.02
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.30
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Fas, PCNA) signal transduction (Fasl, Fas) extracellular region (Fasl, Fas)
plasma membrane (Fasl, Fas) nucleus (Fas, PCNA) nucleoplasm (PCNA)
Fasl (Mus musculus)
Fas (Rattus norvegicus)
PCNA (Homo sapiens)
Pain Link Frequency Relevance Heat
cerebral cortex 9 67.28 Quite High
Hippocampus 1 22.00 Low Low
metalloproteinase 4 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 74 86.04 High High
Neurodegenerative Disease 8 73.52 Quite High
Suicidal Behaviour 27 50.00 Quite Low
Convulsion 1 22.36 Low Low
Cancer 4 20.60 Low Low
Reprotox - General 1 1 8.40 Low Low
Death 17 5.00 Very Low Very Low Very Low
Adhesions 4 5.00 Very Low Very Low Very Low
Repression 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, estrogen decreases Fas expression, and following the activation of Fas by soluble Fas-ligand (sFasL), estrogen suppresses expression of p21/Waf-1/Cip-1 and the proliferating cell nuclear antigen (PCNA).
sFasL Positive_regulation (activation) of Fas Positive_regulation (following) of Gene_expression (expression) of PCNA
1) Confidence 0.02 Published 2004 Journal BMC Neurosci Section Body Doc Link PMC395829 Disease Relevance 0.30 Pain Relevance 0.03

General Comments

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