INT176256

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Context Info
Confidence 0.04
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.35
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Fas) aging (Fas) extracellular region (Fas)
plasma membrane (Fas) nucleus (Fas) cytoplasm (Fas)
Anatomy Link Frequency
smooth muscle cells 2
p53-ps (Rattus norvegicus)
Fas (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cerebral cortex 9 5.00 Very Low Very Low Very Low
metalloproteinase 4 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
Hippocampus 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 74 97.24 Very High Very High Very High
Cancer 4 93.84 High High
Suicidal Behaviour 27 86.08 High High
Death 17 76.40 Quite High
Neurodegenerative Disease 8 5.00 Very Low Very Low Very Low
Adhesions 4 5.00 Very Low Very Low Very Low
Repression 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Demyelinating Disease 1 5.00 Very Low Very Low Very Low
Cv General 4 Under Development 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The transcription factor p53 induces Fas gene transcription [33], the translocation of Fas from Golgi complex to cell surface [34], and activates Fas-mediated apoptosis in un-transformed vascular smooth muscle cells [34] and mammary epithelial tumors [35].
p53 Positive_regulation (induces) of Localization (translocation) of Fas in smooth muscle cells associated with cancer and apoptosis
1) Confidence 0.04 Published 2004 Journal BMC Neurosci Section Body Doc Link PMC395829 Disease Relevance 0.35 Pain Relevance 0

General Comments

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