INT176261

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Context Info
Confidence 0.65
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.97
Pain Relevance 0.82

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (DDAH2)
Anatomy Link Frequency
neuroblasts 1
DDAH2 (Homo sapiens)
Pain Link Frequency Relevance Heat
qutenza 130 99.30 Very High Very High Very High
Bioavailability 1 87.04 High High
Inflammation 8 40.96 Quite Low
Inflammatory response 3 38.52 Quite Low
cytokine 3 32.64 Quite Low
cerebral cortex 9 5.00 Very Low Very Low Very Low
ischemia 5 5.00 Very Low Very Low Very Low
agonist 5 5.00 Very Low Very Low Very Low
abdominal pain 4 5.00 Very Low Very Low Very Low
metalloproteinase 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cardiovascular Disease 1 95.76 Very High Very High Very High
Atherosclerosis 1 93.44 High High
Cancer 48 89.64 High High
Critical Illness 2 88.84 High High
Stress 5 87.96 High High
Sepsis 46 80.80 Quite High
Increased Venous Pressure Under Development 2 77.76 Quite High
Apoptosis 94 75.68 Quite High
Recurrence 3 73.20 Quite High
Sprains And Strains 105 71.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For the family A, 12 different alleles for hspA (designated H6a, H6b, H6c, H6d; H7; H8a, H8b, H8c; H9, H10a, H10b, H10c) and six different alleles for glmM (designated G5, G6a, G6b, G7, G8a, G8b) were distinguished.
Gene_expression (designated) of G6a
1) Confidence 0.65 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2375058 Disease Relevance 0.27 Pain Relevance 0
The expression of cell cycle elements that regulate S-phase [proliferating cell nuclear antigen (PCNA)], the G1/S transition [cyclin dependent kinase 2 (cdk2) and cyclin E], the G2/M transition [cyclin dependent kinase (cdk1) and cyclin A], and a cell cycle arrest factor [p21/wild-type p53-activated fragment (Waf1)/Cip1 (cdk-interacting protein-1)], and Fas were verified by western immunoblot analysis of E15 cortical neuroblasts, according to our previously published protocols [9,37,93,94].
Gene_expression (expression) of S-phase in neuroblasts
2) Confidence 0.58 Published 2004 Journal BMC Neurosci Section Body Doc Link PMC395829 Disease Relevance 0 Pain Relevance 0
These observations seemed to suggest that the anti-proliferative effect of capsaicin was correlated with a decrease in levels of E2F responsive S-phase genes in vivo.


Gene_expression (levels) of S-phase associated with qutenza
3) Confidence 0.58 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2857654 Disease Relevance 0.74 Pain Relevance 0.78
DDAH II has an expression pattern similar to that of endothelial NOS [43].
Gene_expression (expression) of DDAH II
4) Confidence 0.16 Published 2007 Journal Crit Care Section Body Doc Link PMC2206506 Disease Relevance 0.96 Pain Relevance 0.04

General Comments

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