INT176329

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Context Info
Confidence 0.72
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.14
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (MUC1) plasma membrane (MUC1) nucleus (MUC1)
cytoplasm (MUC1)
MUC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
tolerance 5 100.00 Very High Very High Very High
corticosteroid 2 98.92 Very High Very High Very High
Inflammation 14 86.56 High High
Central nervous system 1 30.12 Quite Low
fibrosis 19 5.00 Very Low Very Low Very Low
imagery 10 5.00 Very Low Very Low Very Low
peptic ulcer disease 8 5.00 Very Low Very Low Very Low
positron emission tomography 7 5.00 Very Low Very Low Very Low
cytokine 7 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sprains And Strains 54 98.40 Very High Very High Very High
Immunization 7 93.56 High High
Mycobacterial Infection 1 93.32 High High
Colon Cancer 1 92.04 High High
Autoimmune Disease 6 91.40 High High
Lung Cancer 2 91.08 High High
Breast Cancer 12 89.76 High High
Targeted Disruption 4 88.88 High High
Interstitial Lung Diseases 32 88.20 High High
INFLAMMATION 19 86.56 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
mice, demonstrating a degree of tolerance to MUC1 at the level of
Protein_catabolism (degree) of MUC1 associated with tolerance
1) Confidence 0.72 Published 2003 Journal J Biomed Biotechnol Section Body Doc Link PMC400208 Disease Relevance 0.86 Pain Relevance 0.09
Binding to H. pylori strain J99wt was greatest at 6h (Figure 5E) suggesting the bacteria may be capable of degrading or shedding bound MUC1.
Protein_catabolism (degrading) of MUC1 associated with sprains and strains
2) Confidence 0.64 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2752161 Disease Relevance 0.40 Pain Relevance 0
Decreased MUC1 in the culture medium in infected cultures suggests that substantial amounts of MUC1 was either bound to the bacteria (which were removed by centrifugation prior to ELISA) and/or was degraded.
Protein_catabolism (degraded) of MUC1
3) Confidence 0.56 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2752161 Disease Relevance 0.22 Pain Relevance 0
The concentration of KL-6 was measured one week before and, 1 and 3 weeks after start of treatment.
Protein_catabolism (concentration) of KL-6
4) Confidence 0.36 Published 2010 Journal Respir Res Section Body Doc Link PMC2907324 Disease Relevance 0.65 Pain Relevance 0.05

General Comments

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