INT176372

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Context Info
Confidence 0.16
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.36
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (IL18) extracellular space (IL18) extracellular region (IL18)
cell-cell signaling (IL18) cytoplasm (IL18)
Anatomy Link Frequency
Th1 cells 2
IL18 (Homo sapiens)
IFNA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 5 89.20 High High
rheumatoid arthritis 99 79.76 Quite High
cytokine 17 73.72 Quite High
methotrexate 4 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Crohn's disease 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 6 89.20 High High
Rheumatoid Arthritis 99 79.76 Quite High
Disease 6 5.00 Very Low Very Low Very Low
Adhesions 4 5.00 Very Low Very Low Very Low
Mycobacterial Infection 4 5.00 Very Low Very Low Very Low
Aging 2 5.00 Very Low Very Low Very Low
Opportunistic Infections 1 5.00 Very Low Very Low Very Low
Frailty 1 5.00 Very Low Very Low Very Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 1 5.00 Very Low Very Low Very Low
Autoimmune Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, later studies showed that exogenous IL-18 in the absence of IL-12 failed to drive the differentiation of naive T cells to Th1 cells [16] and that IL-18 was a potent inducer of IFN-?
Positive_regulation (potent) of IL-18 Positive_regulation (inducer) of IFN in Th1 cells
1) Confidence 0.16 Published 2004 Journal Arthritis Res Ther Section Body Doc Link PMC400411 Disease Relevance 0.36 Pain Relevance 0.28

General Comments

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