INT176543

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Context Info
Confidence 0.31
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.57
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Cd44, Spp1) cytoplasm (Cd44, Spp1) extracellular space (Spp1)
extracellular region (Spp1) Golgi apparatus (Cd44) plasma membrane (Cd44)
Anatomy Link Frequency
band 1
Cd44 (Mus musculus)
Spp1 (Mus musculus)
Pain Link Frequency Relevance Heat
alcohol 3 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Tendonitis 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 88 79.36 Quite High
Targeted Disruption 7 67.12 Quite High
Fracture Healing 1 63.56 Quite High
Hypercalcemia 3 59.72 Quite High
Osteoporosis 39 53.88 Quite High
Metastasis 61 50.00 Quite Low
Obesity 1 43.76 Quite Low
Necrosis 2 34.76 Quite Low
Peripheral Arterial Disease 11 24.08 Low Low
Breast Cancer 17 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The interaction of Opn with integrins and CD44 activates several different signaling pathways during the differentiation process [17].
CD44 Binding (interaction) of Opn
1) Confidence 0.31 Published 2010 Journal Cancer Cell Int Section Body Doc Link PMC2984396 Disease Relevance 0.24 Pain Relevance 0
Likewise, Zohar and colleagues have shown that OPN may bind with an ezrin–radixin–moesin complex (band 4.1 proteins) in cooperation with CD44, in order to stimulate cytoskeleton remodeling, signaling, and migration [51].
CD44 Binding (bind) of OPN in band
2) Confidence 0.21 Published 2004 Journal Breast Cancer Res Section Body Doc Link PMC400667 Disease Relevance 0.34 Pain Relevance 0

General Comments

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