INT176561

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Context Info
Confidence 0.25
First Reported 2004
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.38
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Cyp17a1) endoplasmic reticulum (Cyp17a1)
Cyp17a1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
tolerance 2 70.56 Quite High
alcohol 1 16.88 Low Low
Inflammation 4 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
Crohn's disease 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 37 98.92 Very High Very High Very High
Autoimmune Hepatitis 169 93.60 High High
Liver Disease 9 91.28 High High
Primary Sclerosing Cholangitis 7 84.92 Quite High
Obesity 7 78.64 Quite High
Autoimmune Disease 10 76.80 Quite High
Hepatitis 18 59.04 Quite High
Endometriosis (extended) 11 56.08 Quite High
Hepatitis C Virus Infection 43 52.16 Quite High
Infection 17 51.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The detection of 17(OH)7DHP in pig adrenals but not in those of rats is consistent with expression of CYP17 in the former but not latter species [28], [29].
Gene_expression (expression) of CYP17
1) Confidence 0.25 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2629546 Disease Relevance 0 Pain Relevance 0
CYP1A2, CYP2A6, CYP21, CYP17, and CYP11A1), that are expressed in organs affected by the disease process.
Gene_expression (expressed) of CYP17 associated with disease
2) Confidence 0.20 Published 2004 Journal J Autoimmune Dis Section Body Doc Link PMC544946 Disease Relevance 1.25 Pain Relevance 0.04
There were no interactions between treatment group and CYP17 or CYP19 genotypes.


Gene_expression (genotypes) of CYP17
3) Confidence 0.18 Published 2004 Journal Breast Cancer Res Section Body Doc Link PMC400670 Disease Relevance 0.13 Pain Relevance 0

General Comments

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