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Context Info
Confidence 0.41
First Reported 2002
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.85
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

translation factor activity, nucleic acid binding (EEF1A2) nucleus (EEF1A2) translation (EEF1A2)
GTPase activity (EEF1A2) cytoplasm (EEF1A2)
Anatomy Link Frequency
plasma 1
EEF1A2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Bioavailability 2 95.36 Very High Very High Very High
Inflammation 20 89.88 High High
rheumatoid arthritis 4 80.52 Quite High
Arthritis 2 76.28 Quite High
COX-2 inhibitor 2 49.48 Quite Low
ischemia 5 35.28 Quite Low
withdrawal 4 14.08 Low Low
Neuropeptide 25 5.00 Very Low Very Low Very Low
cva 13 5.00 Very Low Very Low Very Low
drug abuse 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Increased Venous Pressure Under Development 59 94.40 High High
General Immunology 4 94.00 High High
INFLAMMATION 22 89.88 High High
Adhesions 9 86.04 High High
Rheumatoid Arthritis 7 80.52 Quite High
Hypertension 7 63.28 Quite High
Infection 33 61.92 Quite High
Malaria 41 42.92 Quite Low
Coronary Artery Disease 58 41.20 Quite Low
Pressure And Volume Under Development 10 40.72 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Statins prevent downregulation of endothelial nitric oxide synthase and may directly upregulate its activity, leading to increased bioavailability of nitric oxide.
Negative_regulation (prevent) of Statins associated with bioavailability
1) Confidence 0.41 Published 2008 Journal Clinical Interventions in Aging Section Body Doc Link PMC2546474 Disease Relevance 0.63 Pain Relevance 0.24
Statins efficiently reduce plasma LDL cholesterol, an effect that may account for their beneficial effect on endothelial function, but they also reduce cellular levels of isoprenoid compounds relevant for the bioavailability of NO.
Negative_regulation (reduce) of Statins in plasma associated with bioavailability
2) Confidence 0.41 Published 2010 Journal The Open Neurology Journal Section Body Doc Link PMC2923338 Disease Relevance 0.06 Pain Relevance 0.05
Immunological inactivation of elongation factor-1 alpha in Sf21 cell lysates
Negative_regulation (inactivation) of elongation factor-1 alpha
3) Confidence 0.03 Published 2002 Journal J Insect Sci Section Body Doc Link PMC405832 Disease Relevance 0.16 Pain Relevance 0

General Comments

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