INT177265

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Context Info
Confidence 0.03
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (NR1H4) signal transduction (NR1H4) small molecule metabolic process (CYP3A4)
oxidoreductase activity (CYP3A4) endoplasmic reticulum (CYP3A4) nucleus (NR1H4)
Anatomy Link Frequency
CAR 2
CYP3A4 (Homo sapiens)
NR1H4 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 4 78.16 Quite High
Paracetamol 2 5.00 Very Low Very Low Very Low
Kinase C 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Colon Cancer 4 5.00 Very Low Very Low Very Low
Liver Cancer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, only reference CAR(SV1) was able to bind to the CAR-response elements DR3 of CYP3A4-XREM (Fig. 3C) and DR4(I) of MDR1 -7.8 kb enhancer (data not shown) as a heterodimer with RXR?.


CYP3A4 Binding (heterodimer) of RXR in CAR
1) Confidence 0.03 Published 2004 Journal Nucl Recept Section Body Doc Link PMC406421 Disease Relevance 0 Pain Relevance 0.04
However, only reference CAR(SV1) was able to bind to the CAR-response elements DR3 of CYP3A4-XREM (Fig. 3C) and DR4(I) of MDR1 -7.8 kb enhancer (data not shown) as a heterodimer with RXR?.


CYP3A4 Binding (heterodimer) of RXR in CAR
2) Confidence 0.03 Published 2004 Journal Nucl Recept Section Body Doc Link PMC406421 Disease Relevance 0 Pain Relevance 0.04

General Comments

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