INT177327

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Context Info
Confidence 0.69
First Reported 2004
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 0.08
Pain Relevance 0.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transmembrane transporter activity (SV2A) endoplasmic reticulum (SV2A) cytoplasm (SV2A)
Anatomy Link Frequency
CAR 5
row 1
SV2A (Homo sapiens)
Pain Link Frequency Relevance Heat
substance P 24 100.00 Very High Very High Very High
cytokine 2 82.20 Quite High
Inflammation 2 81.84 Quite High
Neuropeptide 6 80.48 Quite High
Calcitonin gene-related peptide 11 77.84 Quite High
GABAergic 7 74.36 Quite High
Neurotransmitter 31 66.40 Quite High
Kinase C 5 51.04 Quite High
Glutamate 25 39.20 Quite Low
gABA 41 38.76 Quite Low
Disease Link Frequency Relevance Heat
INFLAMMATION 2 81.84 Quite High
Generalized Anxiety Disorder 19 5.00 Very Low Very Low Very Low
Colon Cancer 10 5.00 Very Low Very Low Very Low
Liver Cancer 5 5.00 Very Low Very Low Very Low
Disease 5 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 3 5.00 Very Low Very Low Very Low
Injury 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CITCO did not influence the interaction properties of CAR isoforms SV3, SV4, SV5 and SV6.
Localization (properties) of SV4 in CAR
1) Confidence 0.69 Published 2004 Journal Nucl Recept Section Body Doc Link PMC406421 Disease Relevance 0 Pain Relevance 0
CITCO did not influence the interaction properties of CAR isoforms SV3, SV4, SV5 and SV6.
Localization (properties) of SV5 in CAR
2) Confidence 0.69 Published 2004 Journal Nucl Recept Section Body Doc Link PMC406421 Disease Relevance 0 Pain Relevance 0
CITCO did not influence the interaction properties of CAR isoforms SV3, SV4, SV5 and SV6.
Localization (properties) of SV3 in CAR
3) Confidence 0.69 Published 2004 Journal Nucl Recept Section Body Doc Link PMC406421 Disease Relevance 0 Pain Relevance 0
CITCO did not influence the interaction properties of CAR isoforms SV3, SV4, SV5 and SV6.
Localization (properties) of SV6 in CAR
4) Confidence 0.69 Published 2004 Journal Nucl Recept Section Body Doc Link PMC406421 Disease Relevance 0 Pain Relevance 0
Unexpectedly, even CAR(SV5) which lacks the last 42 residues did not show decreased nuclear localization.
Localization (localization) of SV5 in CAR
5) Confidence 0.60 Published 2004 Journal Nucl Recept Section Body Doc Link PMC406421 Disease Relevance 0 Pain Relevance 0.03
D12 cells expressed both synaptic proteins (SV2 –second row, first panel; Syn –fourth row, first panel), and SP (second and fourth rows, second panel), with co-localization throughout the cell body and neurites (Merge –second and fourth rows, fourth panel).
Localization (localization) of SV2 in row associated with substance p
6) Confidence 0.37 Published 2008 Journal Biological Procedures Online Section Body Doc Link PMC2683550 Disease Relevance 0.08 Pain Relevance 0.59

General Comments

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