INT177400

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Context Info
Confidence 0.03
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.38
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Npy) extracellular region (Npy)
Anatomy Link Frequency
hippocampus 2
RNY1 (Homo sapiens)
Npy (Mus musculus)
Pain Link Frequency Relevance Heat
Hippocampus 13 100.00 Very High Very High Very High
Neuropeptide 10 100.00 Very High Very High Very High
antagonist 2 98.76 Very High Very High Very High
agonist 1 98.44 Very High Very High Very High
gABA 2 75.80 Quite High
cerebral cortex 2 57.56 Quite High
Neurotransmitter 4 50.00 Quite Low
amygdala 3 41.72 Quite Low
Glutamate receptor 13 5.00 Very Low Very Low Very Low
Pyramidal cell 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 3 92.12 High High
Neurodegenerative Disease 4 92.08 High High
Cognitive Disorder 1 65.68 Quite High
Autism 50 58.56 Quite High
Intellectual Impairment 5 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Oligohydramnios 1 5.00 Very Low Very Low Very Low
Tremor 1 5.00 Very Low Very Low Very Low
Chromosome Aberrations 1 5.00 Very Low Very Low Very Low
Convulsion 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Through studies in these mice and through in vitro studies in the presence of selective NPY Y1 receptor agonists and antagonists, Howell et al. [35] demonstrated that the neuroproliferative effect of NPY in the hippocampus is mediated through the neuropeptide Y receptor NPY Y1 (NPY1R).
Y1 Positive_regulation (mediated) of Negative_regulation (effect) of NPY in hippocampus associated with antagonist, neuropeptide, agonist and hippocampus
1) Confidence 0.03 Published 2004 Journal BMC Med Genet Section Body Doc Link PMC411038 Disease Relevance 0.38 Pain Relevance 0.37

General Comments

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