INT177436

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Context Info
Confidence 0.47
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.81
Pain Relevance 0.52

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

hydrolase activity, acting on glycosyl bonds (HPSE) extracellular region (HPSE) cell adhesion (HPSE)
nucleus (HPSE) carbohydrate metabolic process (HPSE) lysosome (HPSE)
Anatomy Link Frequency
a band 1
HPSE (Homo sapiens)
Pain Link Frequency Relevance Heat
Fibrositis 77 99.92 Very High Very High Very High
substance P 16 66.44 Quite High
depression 19 5.00 Very Low Very Low Very Low
antagonist 17 5.00 Very Low Very Low Very Low
bradykinin 3 5.00 Very Low Very Low Very Low
Opioid 3 5.00 Very Low Very Low Very Low
Lasting pain 2 5.00 Very Low Very Low Very Low
Enkephalin 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fibromyalgia 77 99.92 Very High Very High Very High
Stress 16 99.32 Very High Very High Very High
Reprotox - General 1 4 98.72 Very High Very High Very High
Chronic Fatigue Syndrome 67 95.28 Very High Very High Very High
Disease 4 93.52 High High
Confusion 1 56.04 Quite High
Depression 42 50.00 Quite Low
Sperm Disorder 15 50.00 Quite Low
Congenital Anomalies 8 41.04 Quite Low
Pain 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The NEP2 antibody HPA 007876, used in immunocytochemistry studies, recognized a band of approximately 90 kDa, the size expected for the major membrane-bound human NEP2 isoform [32].
HPA Binding (recognized) of in a band
1) Confidence 0.47 Published 2010 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2936315 Disease Relevance 0 Pain Relevance 0.06
Interaction between the HPA and HPG axes in stress-induced amenorrhea suggests that there may be perturbations of these axes in fibromyalgia and CFS that contribute to these stress-related diseases.
HPA Binding (Interaction) of associated with stress, chronic fatigue syndrome, disease, fibrositis and reprotox - general 1
2) Confidence 0.16 Published 2004 Journal Arthritis Res Ther Section Body Doc Link PMC416440 Disease Relevance 1.81 Pain Relevance 0.45

General Comments

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