INT177492

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Context Info
Confidence 0.45
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.25
Pain Relevance 1.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Slc32a1)
Anatomy Link Frequency
testis 1
brain 1
Slc32a1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 78 99.98 Very High Very High Very High
GABAergic 62 99.68 Very High Very High Very High
Neurotransmitter 10 96.40 Very High Very High Very High
gABA 101 93.44 High High
Substantia nigra 73 92.84 High High
Action potential 5 85.68 High High
tetrodotoxin 14 84.36 Quite High
Spinal cord 46 82.80 Quite High
Calcium channel 1 67.72 Quite High
imagery 6 49.64 Quite Low
Disease Link Frequency Relevance Heat
Brain Hemorrhage 6 99.98 Very High Very High Very High
Cv Unclassified Under Development 72 91.80 High High
Disease 16 87.68 High High
Generalized Anxiety Disorder 33 87.24 High High
Middle Cerebral Artery Infarction 3 56.56 Quite High
Anaerobic Bacterial Infections 22 50.00 Quite Low
Death 2 47.60 Quite Low
Central Nervous System Disease 1 11.80 Low Low
Injury 20 6.40 Low Low
Parkinson's Disease 16 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Quantitative analysis revealed a 3-fold increase in the fluorescence intensity of HCR/T at excitatory terminals (vGLUT1) and a 10-fold increase at inhibitory terminals (vGAT) upon stimulation with high potassium (Figure 1B).
Positive_regulation (increase) of vGAT
1) Confidence 0.45 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2991259 Disease Relevance 0.09 Pain Relevance 0.47
Recent studies reported that focal brain ischemia decreases VGAT in the injured brain regions during the 72 hours after reperfusion [40].
Positive_regulation (decreases) of VGAT in brain associated with brain hemorrhage and ischemia
2) Confidence 0.41 Published 2010 Journal Cardiovascular Psychiatry and Neurology Section Body Doc Link PMC2957857 Disease Relevance 0.93 Pain Relevance 0.56
The GABAergic system is also present in postnatal mouse testis: GAD67, VGAT and several GABAA receptor subunits in postnatal mouse testis
Positive_regulation (present) of VGAT in testis associated with gabaergic
3) Confidence 0.17 Published 2004 Journal Reprod Biol Endocrinol Section Body Doc Link PMC416489 Disease Relevance 0.23 Pain Relevance 0.05

General Comments

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