INT177494

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Context Info
Confidence 0.29
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 0.36
Pain Relevance 0.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Slc32a1)
Anatomy Link Frequency
testis 1
synaptic vesicles 1
Slc32a1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
gABA 164 100.00 Very High Very High Very High
GABAergic 41 98.84 Very High Very High Very High
Calcitonin gene-related peptide 4 89.84 High High
Neurotransmitter 38 89.48 High High
anesthesia 2 80.80 Quite High
Serotonin 6 53.60 Quite High
GABA receptor 25 35.20 Quite Low
Spinal cord 118 20.96 Low Low
Ventral tegmentum 3 15.72 Low Low
Hippocampus 7 14.84 Low Low
Disease Link Frequency Relevance Heat
Generalized Anxiety Disorder 41 97.90 Very High Very High Very High
Cancer 2 31.36 Quite Low
Ganglion Cysts 10 5.00 Very Low Very Low Very Low
Pain 7 5.00 Very Low Very Low Very Low
Frailty 6 5.00 Very Low Very Low Very Low
Nociception 4 5.00 Very Low Very Low Very Low
Adhesions 2 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 2 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low
Shock 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
VAChT (vesicular acetylcholine transporter) and Viaat (vesicular inhibitory amino acid transporter, GABA and glycine release) were expected a priori to be DE between MNs and dCINs [15] and were chosen for this reason.
Localization (release) of Viaat associated with gaba
1) Confidence 0.29 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2566599 Disease Relevance 0 Pain Relevance 0.12
VAChT (vesicular acetylcholine transporter) and Viaat (vesicular inhibitory amino acid transporter, GABA and glycine release) were expected a priori to be DE between MNs and dCINs [15] and were chosen for this reason.
Localization (release) of Viaat associated with gaba
2) Confidence 0.27 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2566599 Disease Relevance 0 Pain Relevance 0.12
For immunohistochemistry, immunocytochemistry and Western blot analyses we employed rabbit polyclonal antiserum against GAD, which recognizes both isoforms GAD65 and GAD67 (DPC Biermann, Bad Nauheim, Germany); rabbit polyclonal antiserum against VGAT (SySy Synaptic Systems GmbH, Göttingen, Germany); rabbit polyclonal antiserum against GABAA-?
Localization (antiserum) of VGAT associated with generalized anxiety disorder
3) Confidence 0.22 Published 2004 Journal Reprod Biol Endocrinol Section Body Doc Link PMC416489 Disease Relevance 0.18 Pain Relevance 0.11
In addition, the vesicular inhibitory amino acid transporter (VIAAT), also commonly referred to as VGAT, transports both GABA and glycine into synaptic vesicles for later release into the synapse.
Localization (release) of VIAAT in synaptic vesicles associated with gaba
4) Confidence 0.19 Published 2010 Journal Frontiers in Molecular Neuroscience Section Body Doc Link PMC2866564 Disease Relevance 0 Pain Relevance 0.09
The GABAergic system is also present in postnatal mouse testis: GAD67, VGAT and several GABAA receptor subunits in postnatal mouse testis
Localization (several) of VGAT in testis associated with gabaergic
5) Confidence 0.11 Published 2004 Journal Reprod Biol Endocrinol Section Body Doc Link PMC416489 Disease Relevance 0.18 Pain Relevance 0.05

General Comments

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