INT177508

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Context Info
Confidence 0.27
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.23
Pain Relevance 0.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (CCL21) extracellular region (CCL21) cell-cell signaling (CCL21)
CCL21 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 24 81.40 Quite High
chemokine 36 79.48 Quite High
Inflammatory response 2 73.84 Quite High
rheumatoid arthritis 6 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
psoriasis 4 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Allergic Dermatitis 42 98.46 Very High Very High Very High
Contact Dermatitis 46 93.36 High High
Skin Diseases 6 81.96 Quite High
INFLAMMATION 26 81.40 Quite High
Disease 6 27.60 Quite Low
Eczema 2 14.16 Low Low
Lichen 2 12.64 Low Low
Inflammatory Bowel Disease 6 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 6 5.00 Very Low Very Low Very Low
Psoriasis 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Around the same time Saeki et al demonstrated that CCL21 production by LEC is crucial for the emigration of murine CCR7+ mature LC from the dermal compartment [1].
Regulation (crucial) of Gene_expression (production) of CCL21
1) Confidence 0.27 Published 2004 Journal BMC Immunol Section Body Doc Link PMC419342 Disease Relevance 0.45 Pain Relevance 0.18
Two patients with Allergic Contact Dermatitis (ACD) were also challenged with the relevant antigen in order to have a positive control for CCL21 expression.
Regulation (control) of Gene_expression (expression) of CCL21 associated with allergic dermatitis
2) Confidence 0.27 Published 2004 Journal BMC Immunol Section Abstract Doc Link PMC419342 Disease Relevance 0.77 Pain Relevance 0.12

General Comments

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