INT177581

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Context Info
Confidence 0.41
First Reported 2004
Last Reported 2010
Negated 43
Speculated 1
Reported most in Body
Documents 113
Total Number 114
Disease Relevance 39.26
Pain Relevance 27.75

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (Fig4) Golgi apparatus (Fig4) endoplasmic reticulum (Fig4)
Anatomy Link Frequency
neurons 9
autonomic 3
meningeal artery 2
brain 2
myocardium 1
Fig4 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
dorsal root ganglion 388 100.00 Very High Very High Very High
agonist 243 100.00 Very High Very High Very High
Hyperalgesia 201 100.00 Very High Very High Very High
Calcitonin gene-related peptide 182 100.00 Very High Very High Very High
Acupuncture 120 100.00 Very High Very High Very High
chemokine 65 100.00 Very High Very High Very High
lidocaine 27 99.98 Very High Very High Very High
Nerve growth factor 163 99.96 Very High Very High Very High
Pyramidal cell 161 99.88 Very High Very High Very High
corticosteroid 94 99.84 Very High Very High Very High
Disease Link Frequency Relevance Heat
Injury 953 100.00 Very High Very High Very High
Ganglion Cysts 512 100.00 Very High Very High Very High
Hyperalgesia 259 100.00 Very High Very High Very High
Increased Venous Pressure Under Development 216 100.00 Very High Very High Very High
Urological Neuroanatomy 202 100.00 Very High Very High Very High
Cancer 114 100.00 Very High Very High Very High
Polycystic Ovary Syndrome 62 100.00 Very High Very High Very High
Aggression 29 100.00 Very High Very High Very High
Aging 29 100.00 Very High Very High Very High
Congenital Anomalies 19 100.00 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
During the 3 unsignaled footshocks, intra-MGN lidocaine affected neither postshock freezing nor USV responses of the RMGN(LI)-FE rats (Fig.
Regulation (affected) of Fig associated with lidocaine
1) Confidence 0.41 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2995742 Disease Relevance 0.45 Pain Relevance 0.34
As seen, for example, in Fig. 2 the variation in the rise time affects the thalamic and
                       cortical responses more than variation in the stimulus amplitude. 
Regulation (affects) of Fig
2) Confidence 0.36 Published 2009 Journal PLoS Computational Biology Section Body Doc Link PMC2653726 Disease Relevance 0 Pain Relevance 0
Materials and
                   Methods), and the number of eigenvalues in Fig. 8 is thus nine for the recurrent model,
                   seven for the feedforward model, and eleven for the full model.
Regulation (eigenvalues) of Fig
3) Confidence 0.36 Published 2009 Journal PLoS Computational Biology Section Body Doc Link PMC2653726 Disease Relevance 0 Pain Relevance 0
In this VC room, the trauma surgeons have remote control of the cameras in Spitsbergen (Fig. 2), and biological parameters are shown on a separate screen.
Regulation (control) of Fig associated with injury
4) Confidence 0.36 Published 2009 Journal World J Surg Section Body Doc Link PMC2691934 Disease Relevance 0.86 Pain Relevance 0
TCs recorded from PA rats' A1 neurons were significantly broader than those derived from controls (Fig. 4A).
Regulation (controls) of Fig in A1 neurons associated with asphyxia
5) Confidence 0.35 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3009724 Disease Relevance 0.52 Pain Relevance 0.04
Further work has to be done in order to improve two different aspects of MAUDS: (1) the adaptive capabilities of the proposed method, by automatically setting the window size of the fast EMA, that can be done based on local membrane potential variability, or exploring ranges of values where the separation remains stable; and (2) a complete validation of MAUDS over an extensive set of intracellular and extracellular data (Fig.
Regulation (ranges) of Fig
6) Confidence 0.34 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1964538 Disease Relevance 0 Pain Relevance 0
No significant change was observed for other indices (Fig. 2).


Neg (No) Regulation (change) of Fig
7) Confidence 0.33 Published 2007 Journal Evidence-based Complementary and Alternative Medicine Section Body Doc Link PMC1810365 Disease Relevance 0.86 Pain Relevance 1.07
The other three indices did not change significantly (Fig. 3: 2A, B and D).
Neg (not) Regulation (change) of Fig
8) Confidence 0.33 Published 2007 Journal Evidence-based Complementary and Alternative Medicine Section Body Doc Link PMC1810365 Disease Relevance 0.76 Pain Relevance 0.96
Tail hang test showed that delayed postconditioning significantly attenuated the percentage of large right turns in control ischemic rats (Fig. 5C).
Regulation (control) of Fig in Tail
9) Confidence 0.31 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2588536 Disease Relevance 0.68 Pain Relevance 0.11
ACC lesions decreased the amount of time spent engaged in social interaction between two adult rats, but had no significant effect on aggression (Fig. 4).
Neg (no) Regulation (effect) of Fig associated with aggression and anterior cingulate cortex
10) Confidence 0.30 Published 2007 Journal The European Journal of Neuroscience Section Body Doc Link PMC2228395 Disease Relevance 0.19 Pain Relevance 0.14
Hg2+ treatment had a biphasic, dose-dependent effect on urine volume (Fig. 1A).
Regulation (effect) of Fig in urine
11) Confidence 0.29 Published 2007 Journal BMC Physiol Section Body Doc Link PMC1810561 Disease Relevance 0.11 Pain Relevance 0.05
For instance, the fact that a low dose of citalopram is already effective on postsynaptic targets when co-administered with a 5-HT4 agonist (Fig. 2) opens the perspective of reducing the doses of SSRI administered, in order to reduce side-effects as well.
Regulation (effective) of Fig associated with agonist and ssri
12) Confidence 0.28 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2821932 Disease Relevance 0.08 Pain Relevance 0.50
However, disconnecting the entorhinal cortex (Fig. 2A) from the hippocampus with a scalpel cut, in a group of five temporal slices, did not measurably affect ongoing SPW mean rate and power (Fig. 2B,C).
Neg (not) Regulation (affect) of Fig in cortex associated with hippocampus
13) Confidence 0.27 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2770848 Disease Relevance 0 Pain Relevance 0.22
Menthol by itself had no effect on the resting membrane current (Fig. 2A and 2B) at low concentrations (?
Neg (no) Regulation (effect) of Fig
14) Confidence 0.26 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2560999 Disease Relevance 0.06 Pain Relevance 0.29
12, vs. control) (Fig. 6C).
Regulation (control) of Fig
15) Confidence 0.26 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2690691 Disease Relevance 0 Pain Relevance 0.04
The present results show that heart and respiratory rates were not greatly affected by fentanyl administration (Fig. 7), and there was no affect on blood gas analysis (table 1).
Neg (not) Regulation (affected) of Fig in respiratory
16) Confidence 0.26 Published 2010 Journal Mol Pain Section Body Doc Link PMC2819047 Disease Relevance 0.46 Pain Relevance 0.89
-TCP increased working time and reduced cement paste viscosity, but did not affect the longevity of the cement/fibrin interface (Fig. 4c).


Neg (not) Regulation (affect) of Fig associated with aging
17) Confidence 0.26 Published 2010 Journal Ann Biomed Eng Section Body Doc Link PMC2871103 Disease Relevance 0.35 Pain Relevance 0
min after the anoxic depolarization (Fig. 3B–C; P?
Regulation (after) of Fig
18) Confidence 0.25 Published 2010 Journal Brain Section Body Doc Link PMC2995884 Disease Relevance 0.32 Pain Relevance 0.11
The 3 h betaine plus ethanol versus ethanol comparison was subjected to data mining to determine which specific genes were down regulated in the metabolic pathways and other pathways (Fig. 4).
Regulation (regulated) of Fig
19) Confidence 0.24 Published 2010 Journal Genes Nutr Section Body Doc Link PMC2988994 Disease Relevance 0.16 Pain Relevance 0.25
Chemokine (c-x-c) ligand 13 was down regulated (Table 3), which is a reflection of the down regulation of the chemokine signaling pathway (Fig. 3).
Regulation (regulation) of Fig associated with chemokine
20) Confidence 0.24 Published 2010 Journal Genes Nutr Section Body Doc Link PMC2988994 Disease Relevance 0.52 Pain Relevance 0.27

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