INT177610

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Context Info
Confidence 0.04
First Reported 2004
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.91
Pain Relevance 0.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
muscle 4
Fbxo23 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Potency 4 98.24 Very High Very High Very High
alcohol 109 83.16 Quite High
withdrawal 13 60.12 Quite High
Physical dependence 8 57.12 Quite High
nMDA receptor 4 53.16 Quite High
drug abuse 68 50.00 Quite Low
tolerance 4 21.16 Low Low
addiction 152 5.00 Very Low Very Low Very Low
Opioid 18 5.00 Very Low Very Low Very Low
Nicotine 14 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sleep Disorders 9 78.96 Quite High
Toxicity 13 67.32 Quite High
Overdose 13 61.32 Quite High
Poisoning 2 59.60 Quite High
Drug Dependence 118 57.12 Quite High
Convulsion 9 52.00 Quite High
Alcohol Addiction 11 35.12 Quite Low
Coma 3 16.40 Low Low
Nicotine Addiction 34 5.00 Very Low Very Low Very Low
Disease 27 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Despite its use for this purpose a recent literature review produced no empirical evidence that GHB-induced hormone release yielded any increase in muscle mass.
Positive_regulation (increase) of Localization (release) of GHB in muscle
1) Confidence 0.04 Published 2004 Journal Harm Reduct J Section Body Doc Link PMC419978 Disease Relevance 0.39 Pain Relevance 0.21
Despite its use for this purpose a recent literature review produced no empirical evidence that GHB-induced hormone release yielded any increase in muscle mass.
Positive_regulation (induced) of Localization (release) of GHB in muscle
2) Confidence 0.04 Published 2004 Journal Harm Reduct J Section Body Doc Link PMC419978 Disease Relevance 0.39 Pain Relevance 0.21
The high potency of luteolin for inhibiting GHB uptake suggested that this compound may be effective at increasing the renal clearance of GHB.
Positive_regulation (increasing) of Localization (clearance) of GHB associated with potency
3) Confidence 0.02 Published 2008 Journal AAPS J Section Body Doc Link PMC2574616 Disease Relevance 0.13 Pain Relevance 0.05

General Comments

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