INT17768

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Context Info
Confidence 0.29
First Reported 1983
Last Reported 1994
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 5
Disease Relevance 2.73
Pain Relevance 0.75

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
plasma 1
Hctq1 (Mus musculus)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 4 96.12 Very High Very High Very High
Opioid 2 95.84 Very High Very High Very High
narcan 6 94.96 High High
tolerance 5 77.20 Quite High
anesthesia 2 75.24 Quite High
halothane 1 73.84 Quite High
Angina 1 60.32 Quite High
Endogenous opioid 2 43.84 Quite Low
cva 1 31.28 Quite Low
Disease Link Frequency Relevance Heat
Hypoxia 16 98.36 Very High Very High Very High
Chronic Disease 3 97.40 Very High Very High Very High
Anaemia 3 96.64 Very High Very High Very High
Rheumatoid Arthritis 4 96.12 Very High Very High Very High
Stress 6 88.40 High High
Hypothermia 2 75.00 Quite High
Hemorrhage 4 72.16 Quite High
Body Weight 2 69.96 Quite High
Death 1 69.44 Quite High
Disease 1 66.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Increased hematocrit is a well-studied adaptation to chronic hypoxia and could be acutely initiated by sympathetically mediated splenic contraction.
Positive_regulation (Increased) of hematocrit associated with hypoxia
1) Confidence 0.29 Published 1994 Journal Am. J. Physiol. Section Abstract Doc Link 8203641 Disease Relevance 0.80 Pain Relevance 0.16
We proposed and evaluated three potential mechanisms of this acute adaptation: 1) increased hematocrit (Hct), 2) protein synthesis, and 3) decreased set point for temperature regulation (set point).
Positive_regulation (increased) of hematocrit
2) Confidence 0.29 Published 1994 Journal Am. J. Physiol. Section Abstract Doc Link 8203641 Disease Relevance 0.72 Pain Relevance 0.14
The increase in hematocrit (Hct) in animals that received saline was significant at the end of cooling and during rewarming.
Positive_regulation (increase) of hematocrit
3) Confidence 0.01 Published 1987 Journal J Cardiovasc Surg (Torino) Section Abstract Doc Link 2444597 Disease Relevance 0.21 Pain Relevance 0.11
Exposure of rats to a simulated altitude of 5,000 m for 1 and 3 d caused increases in hematocrit (Hct) and in hemoglobin (Hb) concentration and a decrease in total plasma volume (TPV) in comparison with sea level control animals.
Positive_regulation (increases) of hematocrit in plasma
4) Confidence 0.00 Published 1983 Journal Aviat Space Environ Med Section Abstract Doc Link 6847573 Disease Relevance 0.26 Pain Relevance 0.14
An increase in hematocrit (Hct) greater than 5 was seen in 4 patients after 4 weeks of therapy.
Positive_regulation (increase) of hematocrit
5) Confidence 0.00 Published 1991 Journal J. Rheumatol. Section Abstract Doc Link 1941817 Disease Relevance 0.74 Pain Relevance 0.19

General Comments

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