INT177760

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.57
First Reported 2004
Last Reported 2010
Negated 1
Speculated 1
Reported most in Body
Documents 21
Total Number 21
Disease Relevance 16.61
Pain Relevance 2.89

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
plasma 2
Monocyte 2
lymphocyte 2
spleen 2
regulatory T cells 2
IFN1@ (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 238 100.00 Very High Very High Very High
Central nervous system 135 99.86 Very High Very High Very High
cINOD 15 99.70 Very High Very High Very High
rheumatoid arthritis 9 99.50 Very High Very High Very High
aspirin 41 98.40 Very High Very High Very High
tolerance 44 95.28 Very High Very High Very High
chemokine 32 94.48 High High
Inflammation 115 93.52 High High
Arthritis 23 88.24 High High
fibrosis 9 61.36 Quite High
Disease Link Frequency Relevance Heat
Mycobacterial Infection 116 100.00 Very High Very High Very High
Conjunctivitis 10 99.70 Very High Very High Very High
Keloid Scars 13 99.52 Very High Very High Very High
Rheumatoid Arthritis 9 99.50 Very High Very High Very High
Syndrome 133 99.34 Very High Very High Very High
Infection 275 99.30 Very High Very High Very High
Myelodysplastic Syndromes 38 99.20 Very High Very High Very High
Sprains And Strains 91 98.96 Very High Very High Very High
Chlamydia Infection 281 98.64 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 275 97.80 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
HIV-infected individuals have defects in cell-mediated immunity including decreased lymphocyte proliferation and decreased production of IL-12 and IFN-?
Negative_regulation (decreased) of Gene_expression (production) of IFN in lymphocyte associated with acquired immune deficiency syndrome or hiv infection
1) Confidence 0.57 Published 2004 Journal Kinetoplastid Biol Dis Section Body Doc Link PMC420481 Disease Relevance 2.19 Pain Relevance 0.05
Intradermal injection of Dp significantly increased the expression of IL-4, IL-5, and IL-13 and significantly decreased the expression of IFN-?
Negative_regulation (decreased) of Gene_expression (expression) of IFN
2) Confidence 0.57 Published 2010 Journal Environ Health Perspect Section Body Doc Link PMC2854722 Disease Relevance 0.17 Pain Relevance 0.22
CD4+CD25high regulatory T cells from RA subjects are capable of suppressing the production of IFN-?
Negative_regulation (suppressing) of Gene_expression (production) of IFN in regulatory T cells associated with rheumatoid arthritis
3) Confidence 0.57 Published 2008 Journal Pediatr Rheumatol Online J Section Body Doc Link PMC2633304 Disease Relevance 0.80 Pain Relevance 0.41
In particular we hypothesized that Beijing strains elicit a weaker Th1 immune response, as shown by a reduced production of plasma IFN-?.


Negative_regulation (reduced) of Gene_expression (production) of IFN in plasma associated with sprains and strains
4) Confidence 0.42 Published 2006 Journal BMC Infect Dis Section Body Doc Link PMC1552074 Disease Relevance 1.28 Pain Relevance 0
Similarly, C3 deficiency associates with a decreased production of IFN-?
Negative_regulation (decreased) of Gene_expression (production) of IFN
5) Confidence 0.42 Published 2010 Journal European Journal of Immunology Section Body Doc Link PMC2988415 Disease Relevance 0.29 Pain Relevance 0.16
There was a correlation with decreased production of IL-12 and IFN-?
Negative_regulation (decreased) of Gene_expression (production) of IFN
6) Confidence 0.42 Published 2004 Journal Kinetoplastid Biol Dis Section Body Doc Link PMC420481 Disease Relevance 1.69 Pain Relevance 0.11
Moreover, the reduction in the IL-10 levels in PbA-infected mice exposed to HBO might be associated with the decrease in expression of IFN-?
Negative_regulation (decrease) of Gene_expression (expression) of IFN
7) Confidence 0.42 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2518956 Disease Relevance 0.69 Pain Relevance 0.07
Moreover, P14 cells in the CNS never lost the ability to produce the antiviral cytokine IFN-?.
Negative_regulation (lost) of Gene_expression (produce) of IFN associated with central nervous system and cytokine
8) Confidence 0.42 Published 2007 Journal Virol J Section Body Doc Link PMC1899484 Disease Relevance 0 Pain Relevance 0.37
Subjects with scarring trachoma have shown to produce reduced IFN-?
Negative_regulation (reduced) of Gene_expression (produce) of IFN associated with conjunctivitis and keloid scars
9) Confidence 0.42 Published 2009 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2695819 Disease Relevance 2.24 Pain Relevance 0.11
in DS are likely to be related to the presence of several IFN receptor genes in chromosome 21 including IFNGR2, which is one of the subunits of the IFN-?
Negative_regulation (presence) of Gene_expression (one) of IFN associated with syndrome
10) Confidence 0.41 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2996288 Disease Relevance 1.12 Pain Relevance 0.05
Moreover, IL-9 inhibits lymphokine production by IFN-?
Negative_regulation (inhibits) of Gene_expression (production) of IFN
11) Confidence 0.41 Published 2010 Journal Journal of Allergy Section Body Doc Link PMC2957587 Disease Relevance 0.34 Pain Relevance 0.03
Samples from 13 vaccine and 5 placebo recipients from groups C and D were assessed using an IL-2/IFN-?
Negative_regulation (assessed) of Gene_expression (using) of IFN
12) Confidence 0.41 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2943475 Disease Relevance 0.06 Pain Relevance 0.08
NSAIDs were shown to inhibit T cell proliferation, expression of activation-related molecules such as CD25 and CD71, and the production of cytokines such as IL-2, IFN-?
Negative_regulation (inhibit) of Gene_expression (production) of IFN in T cell associated with cinod and cytokine
13) Confidence 0.41 Published 2010 Journal Immune Network Section Body Doc Link PMC2902675 Disease Relevance 0.32 Pain Relevance 1.01
Monocyte-derived activated killer (MAK) cells are autologous, highly purified, IFN?
Negative_regulation (purified) of Gene_expression (autologous) of IFN in Monocyte
14) Confidence 0.41 Published 2010 Journal J Transl Med Section Body Doc Link PMC2893125 Disease Relevance 0.75 Pain Relevance 0.08
Specifically, 5 of 22 HLA-A2 and/or HLA-A3 volunteers developed PfCS102 specific IFN-?
Negative_regulation (developed) of Gene_expression (specific) of IFN
15) Confidence 0.41 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2749339 Disease Relevance 0.23 Pain Relevance 0
g CIFN tiw, 232 patients received 9 ?
Negative_regulation (received) of Gene_expression (tiw) of IFN
16) Confidence 0.41 Published 2008 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2727894 Disease Relevance 0.33 Pain Relevance 0
TH1 responses are classically defined by the production of interferon (IFN)-?
Negative_regulation (defined) of Gene_expression (production) of IFN
17) Confidence 0.41 Published 2009 Journal Journal of Oncology Section Body Doc Link PMC2723756 Disease Relevance 0.72 Pain Relevance 0.04
Indeed, we have previously shown that filarial infection coincident with Mtb significantly diminishes Mtb-specific Th1 (IL-12/IFN-?)
Negative_regulation (diminishes) of Gene_expression (/) of IFN associated with mycobacterial infection and infection
18) Confidence 0.41 Published 2009 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2710006 Disease Relevance 1.16 Pain Relevance 0.08
Relative expression of IFN-?
Negative_regulation (Relative) of Gene_expression (expression) of IFN
19) Confidence 0.41 Published 2009 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2695819 Disease Relevance 0.89 Pain Relevance 0
When spleen cells cultured without Con A, the production of IL-2 and IFN-?
Negative_regulation (cultured) of Gene_expression (production) of IFN in spleen
20) Confidence 0.41 Published 2005 Journal BMC Complement Altern Med Section Body Doc Link PMC1084244 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox