INT177790

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Context Info
Confidence 0.10
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (MTF1, NR2F1) nucleoplasm (NR2F1) signal transduction (NR2F1)
nucleolus (MTF1) intracellular (MTF1) DNA binding (MTF1)
Anatomy Link Frequency
Caco-2 1
MTF1 (Homo sapiens)
NR2F1 (Homo sapiens)
Pain Link Frequency Relevance Heat
aspirin 5 5.00 Very Low Very Low Very Low
Inflammation 5 5.00 Very Low Very Low Very Low
cINOD 4 5.00 Very Low Very Low Very Low
COX2 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Colon Cancer 40 50.00 Quite Low
Apoptosis 11 5.00 Very Low Very Low Very Low
Cancer 9 5.00 Very Low Very Low Very Low
INFLAMMATION 5 5.00 Very Low Very Low Very Low
Hypersensitivity 5 5.00 Very Low Very Low Very Low
Adhesions 4 5.00 Very Low Very Low Very Low
Leukemia 3 5.00 Very Low Very Low Very Low
Stomach Cancer 2 5.00 Very Low Very Low Very Low
Reprotox - General 1 2 5.00 Very Low Very Low Very Low
Adenoma 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In Caco-2 cells several transcription factors were upregulated by curcumin, like NR2F1, NR4A1 and MTF1, whereas transcription factor FOSB and transcription-related genes HNRPA0 and POLR1C were downregulated (Table 3).
MTF1 Positive_regulation (upregulated) of NR2F1 in Caco-2
1) Confidence 0.10 Published 2004 Journal J Carcinog Section Body Doc Link PMC421747 Disease Relevance 0 Pain Relevance 0

General Comments

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