INT177856

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Context Info
Confidence 0.19
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.12
Pain Relevance 0.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (HDAC2) nucleus (HDAC2) enzyme binding (HDAC2)
transcription factor binding (HDAC2) cytoplasm (HDAC2)
HDAC2 (Homo sapiens)
Pain Link Frequency Relevance Heat
aspirin 5 83.88 Quite High
cINOD 4 82.44 Quite High
Inflammation 5 43.96 Quite Low
COX2 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Colon Cancer 40 63.76 Quite High
INFLAMMATION 5 43.96 Quite Low
Metastasis 1 10.56 Low Low
Apoptosis 11 5.00 Very Low Very Low Very Low
Cancer 9 5.00 Very Low Very Low Very Low
Hypersensitivity 5 5.00 Very Low Very Low Very Low
Adhesions 4 5.00 Very Low Very Low Very Low
Leukemia 3 5.00 Very Low Very Low Very Low
Stomach Cancer 2 5.00 Very Low Very Low Very Low
Reprotox - General 1 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In these cells curcumin or demethoxycurcumin upregulated expression of cyclin-dependent kinase inhibitor 2D (p19INK4D) and downregulated expression of PCNA, HDAC2, MAP2K1 and PLAU.
Negative_regulation (downregulated) of Gene_expression (expression) of HDAC2
1) Confidence 0.19 Published 2004 Journal J Carcinog Section Body Doc Link PMC421747 Disease Relevance 0.12 Pain Relevance 0.30

General Comments

This test has worked.

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