INT177869

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Context Info
Confidence 0.65
First Reported 2004
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 2.11
Pain Relevance 0.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

microtubule organizing center (BUB1B) cytoplasm (BUB1B) cytosol (BUB1B)
cell proliferation (BUB1B) mitosis (BUB1B) chromosome (BUB1B)
BUB1B (Homo sapiens)
Pain Link Frequency Relevance Heat
aspirin 5 98.72 Very High Very High Very High
cINOD 4 95.32 Very High Very High Very High
Inflammation 5 94.72 High High
adenocard 1 33.92 Quite Low
peptic ulcer disease 2 5.00 Very Low Very Low Very Low
COX2 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 73 100.00 Very High Very High Very High
INFLAMMATION 5 94.72 High High
Colon Cancer 42 91.52 High High
Lymphatic System Cancer 2 66.88 Quite High
Metastasis 1 61.32 Quite High
Stomach Cancer 4 42.24 Quite Low
Adenocarcinoma 79 38.12 Quite Low
Skin Cancer 4 37.36 Quite Low
Esophageal Cancer 22 31.88 Quite Low
Cleidocranial Dysplasia 16 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As expected, BUB1B was expressed at high levels in the normal esophageal tissues of patients without cancer and underexpressed in patients with cancer.
Gene_expression (underexpressed) of BUB1B associated with cancer
1) Confidence 0.65 Published 2007 Journal Bioinform Biol Insights Section Body Doc Link PMC2323355 Disease Relevance 0.72 Pain Relevance 0
As expected, BUB1B was expressed at high levels in the normal esophageal tissues of patients without cancer and underexpressed in patients with cancer.
Gene_expression (expressed) of BUB1B associated with cancer
2) Confidence 0.65 Published 2007 Journal Bioinform Biol Insights Section Body Doc Link PMC2323355 Disease Relevance 0.65 Pain Relevance 0
For example, expression of ASNS, ATF4 and MTHFD2 was upregulated by sulindac and expression of BUB1B and PDCD2 was downregulated by aspirin.
Gene_expression (expression) of BUB1B associated with aspirin
3) Confidence 0.42 Published 2004 Journal J Carcinog Section Body Doc Link PMC421747 Disease Relevance 0.74 Pain Relevance 0.45

General Comments

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