INT177943

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Context Info
Confidence 0.11
First Reported 2004
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.81
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (MAPK9) nucleoplasm (MAPK9) mitochondrion (MAPK9)
nucleus (MAPK9) transcription factor binding (MAPK9) response to stress (MAPK9)
MAPK9 (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 39 85.72 High High
cINOD 10 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
Paracetamol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 4 99.60 Very High Very High Very High
Apoptosis 42 93.44 High High
Osteoarthritis 40 85.72 High High
Nerve Sheath Neoplasms 22 75.04 Quite High
Osteoporosis 6 66.96 Quite High
Necrosis 1 44.72 Quite Low
Watson Syndrome 19 5.00 Very Low Very Low Very Low
Cancer 17 5.00 Very Low Very Low Very Low
Hypercalcemia 11 5.00 Very Low Very Low Very Low
INFLAMMATION 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SAPK/JNK and caspase-3 activation
Positive_regulation (activation) of Gene_expression (/) of SAPK
1) Confidence 0.11 Published 2004 Journal Cancer Cell Int Section Body Doc Link PMC425591 Disease Relevance 0.44 Pain Relevance 0
also markedly increased the SAPK/JNK (p46 and p54), particularly the level of the p46 isoforms.
Positive_regulation (increased) of Gene_expression (/) of SAPK
2) Confidence 0.10 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2483463 Disease Relevance 0.37 Pain Relevance 0.15

General Comments

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