INT177953

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Context Info
Confidence 0.07
First Reported 2004
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 11
Disease Relevance 2.72
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
macrophages 2
monocytes 2
dendritic cells 2
PBLs 1
B cells 1
BTNL2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 3 83.12 Quite High
cva 18 5.00 Very Low Very Low Very Low
cytokine 9 5.00 Very Low Very Low Very Low
spinal inflammation 9 5.00 Very Low Very Low Very Low
rheumatoid arthritis 9 5.00 Very Low Very Low Very Low
headache 3 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 34 100.00 Very High Very High Very High
Multiple Organ Failure 1 97.48 Very High Very High Very High
Shock 2 96.36 Very High Very High Very High
Pressure Volume 2 Under Development 3 96.08 Very High Very High Very High
Hypopigmentation 32 95.28 Very High Very High Very High
Fever 86 94.80 High High
Streptococcus Infection 31 93.40 High High
INFLAMMATION 3 83.12 Quite High
Sepsis 15 80.44 Quite High
Meningitis 10 80.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We investigated this outbreak of SS2 infections in both human and pigs, which took place from July to August, 2005, through clinical observation and laboratory experiments.
Gene_expression (infections) of SS2 associated with infection
1) Confidence 0.07 Published 2006 Journal PLoS Medicine Section Abstract Doc Link PMC1434494 Disease Relevance 1.39 Pain Relevance 0
In a study of 49 biopsies from the margin of depigmented cutaneous lesions, the expression of Major Histocompatibility Complex class II (MHC-II) antigens demonstrates activation of the infiltrating T cells [11].
Gene_expression (expression) of class II in T cells
2) Confidence 0.02 Published 2004 Journal Lipids Health Dis Section Body Doc Link PMC425594 Disease Relevance 0.95 Pain Relevance 0.04
HLA class II typing is done with B lymphocytes isolated from PBLs because these cells express class II molecules.
Gene_expression (express) of class II in PBLs
3) Confidence 0.01 Published 2007 Journal Yonsei Medical Journal Section Body Doc Link PMC2628004 Disease Relevance 0 Pain Relevance 0
The class I molecule-peptide complex on the cell surface is recognized by the T-cell receptor of CD8+ lymphocytes.15 Class II expression is mainly restricted to the antigen-presenting cells including B cells, monocytes/macrophages, dendritic cells, and Langerhans cells.
Gene_expression (expression) of Class II in dendritic cells
4) Confidence 0.01 Published 2007 Journal Yonsei Medical Journal Section Body Doc Link PMC2628004 Disease Relevance 0 Pain Relevance 0
Class II molecules are expressed only on B lymphocytes, antigen-presenting cells (monocytes, macrophages, and dendritic cells), and activated T lymphocytes.


Gene_expression (expressed) of Class II in dendritic cells
5) Confidence 0.01 Published 2007 Journal Yonsei Medical Journal Section Body Doc Link PMC2628004 Disease Relevance 0.13 Pain Relevance 0
The class I molecule-peptide complex on the cell surface is recognized by the T-cell receptor of CD8+ lymphocytes.15 Class II expression is mainly restricted to the antigen-presenting cells including B cells, monocytes/macrophages, dendritic cells, and Langerhans cells.
Gene_expression (expression) of Class II in B cells
6) Confidence 0.00 Published 2007 Journal Yonsei Medical Journal Section Body Doc Link PMC2628004 Disease Relevance 0 Pain Relevance 0
Class II molecules are expressed only on B lymphocytes, antigen-presenting cells (monocytes, macrophages, and dendritic cells), and activated T lymphocytes.


Gene_expression (expressed) of Class II in macrophages
7) Confidence 0.00 Published 2007 Journal Yonsei Medical Journal Section Body Doc Link PMC2628004 Disease Relevance 0.13 Pain Relevance 0
The class I molecule-peptide complex on the cell surface is recognized by the T-cell receptor of CD8+ lymphocytes.15 Class II expression is mainly restricted to the antigen-presenting cells including B cells, monocytes/macrophages, dendritic cells, and Langerhans cells.
Gene_expression (expression) of Class II in macrophages
8) Confidence 0.00 Published 2007 Journal Yonsei Medical Journal Section Body Doc Link PMC2628004 Disease Relevance 0 Pain Relevance 0
The class I molecule-peptide complex on the cell surface is recognized by the T-cell receptor of CD8+ lymphocytes.15 Class II expression is mainly restricted to the antigen-presenting cells including B cells, monocytes/macrophages, dendritic cells, and Langerhans cells.
Gene_expression (expression) of Class II in Langerhans cells
9) Confidence 0.00 Published 2007 Journal Yonsei Medical Journal Section Body Doc Link PMC2628004 Disease Relevance 0 Pain Relevance 0
Class II molecules are expressed only on B lymphocytes, antigen-presenting cells (monocytes, macrophages, and dendritic cells), and activated T lymphocytes.


Gene_expression (expressed) of Class II in monocytes
10) Confidence 0.00 Published 2007 Journal Yonsei Medical Journal Section Body Doc Link PMC2628004 Disease Relevance 0.13 Pain Relevance 0
The class I molecule-peptide complex on the cell surface is recognized by the T-cell receptor of CD8+ lymphocytes.15 Class II expression is mainly restricted to the antigen-presenting cells including B cells, monocytes/macrophages, dendritic cells, and Langerhans cells.
Gene_expression (expression) of Class II in monocytes
11) Confidence 0.00 Published 2007 Journal Yonsei Medical Journal Section Body Doc Link PMC2628004 Disease Relevance 0 Pain Relevance 0

General Comments

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