INT177956

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Context Info
Confidence 0.49
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.02
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (HLA-E)
Anatomy Link Frequency
embryonic stem cells 2
HLA-E (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 15 83.80 Quite High
cytokine 7 58.48 Quite High
corticosteroid 1 58.28 Quite High
antagonist 16 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
aspirin 2 5.00 Very Low Very Low Very Low
Paracetamol 2 5.00 Very Low Very Low Very Low
COX-2 inhibitor 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Natriuresis 3 95.72 Very High Very High Very High
INFLAMMATION 17 83.80 Quite High
Hypertrophy 22 80.08 Quite High
Hypopigmentation 32 68.52 Quite High
Disease 5 62.48 Quite High
Repression 1 53.96 Quite High
Cancer 1 50.08 Quite High
Skin Cancer 2 49.80 Quite Low
Organ Transplantation 3 49.52 Quite Low
Influenza Virus Infection 1 31.64 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Prolonged resistance training has been reported to increase the mRNA and protein expression of the MHC type IIa isoform while decreasing type IIx and minimally altering type I isoform expression patterns [43].
Positive_regulation (increase) of Transcription (expression) of MHC
1) Confidence 0.49 Published 2007 Journal J Int Soc Sports Nutr Section Body Doc Link PMC2217562 Disease Relevance 0.42 Pain Relevance 0.16
induced MHC-II expression (mRNA and protein) through actions on the CIITA promoter I [17].
Positive_regulation (induced) of Transcription (expression) of MHC
2) Confidence 0.09 Published 2004 Journal Lipids Health Dis Section Body Doc Link PMC425594 Disease Relevance 0.35 Pain Relevance 0.03
The increase in the mRNA expression of the cardiac-specific transcription factor Nkx2.5 and cardiac markers MLC2 and MHC followed treatment of embryonic stem cells with NO donors and cGMP activators [32].
Positive_regulation (increase) of Transcription (expression) of MHC in embryonic stem cells
3) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2964328 Disease Relevance 0.24 Pain Relevance 0

General Comments

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