INT177970

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Context Info
Confidence 0.20
First Reported 2004
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.62
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL5) extracellular region (IL5)
IL5 (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 28 99.12 Very High Very High Very High
Inflammation 98 86.04 High High
cytokine 105 84.36 Quite High
fibrosis 2 73.04 Quite High
dexamethasone 2 56.96 Quite High
antagonist 34 5.00 Very Low Very Low Very Low
agonist 20 5.00 Very Low Very Low Very Low
nud 7 5.00 Very Low Very Low Very Low
Inflammatory response 6 5.00 Very Low Very Low Very Low
methotrexate 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Eosinophilia 46 99.96 Very High Very High Very High
Recurrence 1 87.72 High High
INFLAMMATION 105 86.04 High High
Asthma 318 78.36 Quite High
Metaplasia 6 75.44 Quite High
Fibrosis 2 73.04 Quite High
Disease 42 64.96 Quite High
Hypersensitivity 19 60.88 Quite High
Occupational Lung Diseases 16 60.16 Quite High
Gastritis 20 57.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Glucocorticoids, the most effective agents for reducing eosinophilia, suppress the gene transcription of IL-3, IL-4, IL-5, GM-CSF, and various chemokines [1].
Negative_regulation (suppress) of Transcription (transcription) of IL-5 associated with chemokine and eosinophilia
1) Confidence 0.20 Published 2004 Journal Clin Mol Allergy Section Body Doc Link PMC425596 Disease Relevance 0.59 Pain Relevance 0.10
B, but this does not account for all effects, as IL-10 is very effective at inhibiting IL-5 transcription, which is independent of NF-?
Negative_regulation (inhibiting) of Transcription (transcription) of IL-5
2) Confidence 0.08 Published 2008 Journal J Occup Med Toxicol Section Body Doc Link PMC2259400 Disease Relevance 1.02 Pain Relevance 0.28

General Comments

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