INT177972

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Context Info
Confidence 0.20
First Reported 2004
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.81
Pain Relevance 0.66

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL3) extracellular region (IL3) cell-cell signaling (IL3)
IL3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 55 100.00 Very High Very High Very High
cytokine 45 100.00 Very High Very High Very High
chemokine 6 100.00 Very High Very High Very High
dexamethasone 44 94.12 High High
agonist 7 76.04 Quite High
Inflammatory response 1 51.84 Quite High
Potency 3 9.44 Low Low
nud 7 5.00 Very Low Very Low Very Low
abdominal pain 5 5.00 Very Low Very Low Very Low
Inflammatory marker 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 59 100.00 Very High Very High Very High
Eosinophilia 27 99.60 Very High Very High Very High
Disease 27 98.38 Very High Very High Very High
Ocular Hypertension 7 91.92 High High
Recurrence 1 87.00 High High
Adhesions 9 82.88 Quite High
Glaucoma 2 73.24 Quite High
Disorders Of The Lacrimal System 3 68.32 Quite High
Hypersensitivity 14 67.36 Quite High
Ocular Toxicity (including Many Sub-types) 2 62.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Glucocorticoids, the most effective agents for reducing eosinophilia, suppress the gene transcription of IL-3, IL-4, IL-5, GM-CSF, and various chemokines [1].
Transcription (transcription) of IL-3 associated with chemokine and eosinophilia
1) Confidence 0.20 Published 2004 Journal Clin Mol Allergy Section Body Doc Link PMC425596 Disease Relevance 0.53 Pain Relevance 0.10
Although the glucocorticoid action in inflammatory diseases is not fully understood, it is well documented that glucocorticoids inhibit the transcription of the majority of inflammatory cytokines and chemokines involved in the inflammatory process, including eotaxin, GM-CSF, IL-1ß, IL-2, IL-3, IL-4, IL-5, IL-6, IL-8, IL-11, MCP-1, MIP-1, MIP-3, MIP-4, MIP-1?
Transcription (transcription) of IL-3 associated with chemokine, inflammation, disease and cytokine
2) Confidence 0.12 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2790480 Disease Relevance 1.28 Pain Relevance 0.55

General Comments

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