INT177977

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Context Info
Confidence 0.14
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.00
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (CSF1R) signal transduction (CSF1R) nucleolus (RUNX1)
plasma membrane (CSF1R) nucleus (RUNX1) DNA binding (RUNX1)
RUNX1 (Homo sapiens)
CSF1R (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 2 99.08 Very High Very High Very High
psoriasis 1 95.84 Very High Very High Very High
Crohn's disease 40 92.12 High High
Inflammation 5 52.52 Quite High
cytokine 3 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 2 99.08 Very High Very High Very High
Diabetes Mellitus 1 98.08 Very High Very High Very High
Systemic Lupus Erythematosus 1 97.04 Very High Very High Very High
Psoriasis 1 95.84 Very High Very High Very High
Disease Susceptibility 9 91.80 High High
Disease 37 76.36 Quite High
Inflammatory Bowel Disease 5 53.08 Quite High
Adhesions 1 43.80 Quite Low
Fibromyalgia 2 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since the CSF1R gene is a target of RUNX1 and has multiple RUNX1 binding sites in several introns [35], complete sequencing of each of these sites will be performed to investigate the hypothesis that defective RUNX1 binding is related to Crohn's disease susceptibility [36].


RUNX1 Regulation (target) of CSF1R gene associated with disease susceptibility and crohn's disease
1) Confidence 0.14 Published 2004 Journal J Immune Based Ther Vaccines Section Body Doc Link PMC428583 Disease Relevance 1.00 Pain Relevance 0.27

General Comments

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