INT177990

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Context Info
Confidence 0.13
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.07
Pain Relevance 0.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (RUNX1) nucleus (RUNX1) DNA binding (RUNX1)
transcription factor binding (RUNX1)
RUNX1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Crohn's disease 40 98.44 Very High Very High Very High
cytokine 3 94.52 High High
rheumatoid arthritis 2 88.80 High High
Inflammation 5 87.76 High High
psoriasis 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 37 98.12 Very High Very High Very High
Disease Susceptibility 9 93.24 High High
Rheumatoid Arthritis 2 88.80 High High
Inflammatory Bowel Disease 5 88.32 High High
Autoimmune Disease 1 86.80 High High
INFLAMMATION 2 76.52 Quite High
Colitis 1 67.44 Quite High
Fibromyalgia 2 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Weight Loss 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, a missense substitution in SLC22A4, a gene in this region that is a downstream target of the transcription factor, Runx1, is associated with susceptibility to Crohn's disease [11].
Regulation (target) of Runx1 associated with crohn's disease and disease
1) Confidence 0.13 Published 2004 Journal J Immune Based Ther Vaccines Section Body Doc Link PMC428583 Disease Relevance 1.07 Pain Relevance 0.51

General Comments

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