INT1780

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Context Info
Confidence 0.49
First Reported 1977
Last Reported 1993
Negated 1
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.09
Pain Relevance 1.80

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Gh1) signal transduction (Gh1) mitochondrion (Gh1)
extracellular space (Gh1) extracellular region (Gh1) plasma membrane (Gh1)
Anatomy Link Frequency
thyroid 2
Gh1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Morphine 6 99.68 Very High Very High Very High
Clonidine 4 99.32 Very High Very High Very High
narcan 7 97.80 Very High Very High Very High
Catecholamine 1 87.96 High High
Opioid 5 86.24 High High
Somatostatin 7 83.04 Quite High
antagonist 1 82.92 Quite High
opiate 1 82.12 Quite High
Disease Link Frequency Relevance Heat
Decapitation 1 86.56 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Intravenous administration of apomorphine (.03 and .1 mg/kg) had no effect on decreased GH levels, whereas clonidine (150 micrograms/kg) restored GH secretion.
Neg (no) Regulation (effect) of Negative_regulation (decreased) of GH associated with clonidine
1) Confidence 0.49 Published 1977 Journal Endocrinology Section Abstract Doc Link 233821 Disease Relevance 0 Pain Relevance 0.23
The effects of thyroid hormone deprivation and of subsequent replacement therapy on growth hormone (GH) secretion were investigated in unrestrained unanesthetized rats.
Regulation (effects) of Negative_regulation (deprivation) of GH in thyroid
2) Confidence 0.27 Published 1985 Journal Neuroendocrinology Section Abstract Doc Link 2867482 Disease Relevance 0.09 Pain Relevance 0.28
On the other hand, treatment with morphine produced a 22% decrease in GH mRNA levels, an effect which was prevented by the concomitant administration naloxone.
Regulation (effect) of Negative_regulation (decrease) of GH associated with narcan and morphine
3) Confidence 0.14 Published 1993 Journal J. Neuroendocrinol. Section Abstract Doc Link 8680424 Disease Relevance 0 Pain Relevance 1.28

General Comments

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