INT178101

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Context Info
Confidence 0.03
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.00
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (EDN1, BCL2) mitochondrion (BCL2) cell morphogenesis (BCL2)
endoplasmic reticulum (BCL2) intracellular (BCL2) cell-cell signaling (EDN1)
EDN1 (Homo sapiens)
BCL2 (Homo sapiens)
Pain Link Frequency Relevance Heat
withdrawal 1 95.36 Very High Very High Very High
antagonist 29 87.28 High High
metalloproteinase 8 5.00 Very Low Very Low Very Low
Pain 6 5.00 Very Low Very Low Very Low
analgesia 2 5.00 Very Low Very Low Very Low
nociceptor 2 5.00 Very Low Very Low Very Low
Pain refractory 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 16 99.66 Very High Very High Very High
Ovarian Cancer 23 92.80 High High
Cancer 65 84.56 Quite High
Hypoxia 9 36.68 Quite Low
Reprotox - General 1 16 5.00 Very Low Very Low Very Low
Skin Cancer 14 5.00 Very Low Very Low Very Low
Metastasis 13 5.00 Very Low Very Low Very Low
Sarcoma 9 5.00 Very Low Very Low Very Low
Breast Cancer 8 5.00 Very Low Very Low Very Low
Osteoporosis 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Paclitaxel-induced apoptosis resulted in the phosphorylation of Bcl-2 that was suppressed by the addition of ET-1.
ET-1 Negative_regulation (suppressed) of Phosphorylation (phosphorylation) of Bcl-2 associated with apoptosis
1) Confidence 0.03 Published 2004 Journal J Transl Med Section Body Doc Link PMC436068 Disease Relevance 1.00 Pain Relevance 0.12

General Comments

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