INT178190

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Context Info
Confidence 0.27
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.42
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Spa17) cytoplasm (Spa17)
Anatomy Link Frequency
cilia 1
female reproductive systems 1
spermatozoa 1
Spa17 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 27 5.00 Very Low Very Low Very Low
cytokine 24 5.00 Very Low Very Low Very Low
tolerance 12 5.00 Very Low Very Low Very Low
Inflammation 9 5.00 Very Low Very Low Very Low
chemokine 6 5.00 Very Low Very Low Very Low
Pain 6 5.00 Very Low Very Low Very Low
Inflammatory mediators 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 606 90.00 High High
Ovarian Cancer 18 73.16 Quite High
Multiple Myeloma 12 72.40 Quite High
Testicular Cancer 6 59.08 Quite High
Metastasis 12 44.04 Quite Low
Aging 3 31.44 Quite Low
Skin Cancer 48 5.00 Very Low Very Low Very Low
Immunization 24 5.00 Very Low Very Low Very Low
Targeted Disruption 24 5.00 Very Low Very Low Very Low
Death 18 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Because a common origin of cilia and flagella in eukaryotes has been proposed, the expression of Sp17 was investigated in human ciliated epithelia.
Gene_expression (expression) of Sp17 in cilia
1) Confidence 0.27 Published 2004 Journal J Transl Med Section Body Doc Link PMC441417 Disease Relevance 0.46 Pain Relevance 0
Sp17 is strongly expressed in germinal cells and in the flagella of spermatozoa.
Gene_expression (expressed) of Sp17 in spermatozoa
2) Confidence 0.27 Published 2004 Journal J Transl Med Section Body Doc Link PMC441417 Disease Relevance 0.56 Pain Relevance 0
Indeed; Sp17 was detectable in ciliated epithelia of the respiratory airways and both the male and female reproductive systems questioning the usefulness of Sp17 in immunotherapy protocols.
Gene_expression (detectable) of Sp17 in female reproductive systems
3) Confidence 0.27 Published 2004 Journal J Transl Med Section Body Doc Link PMC441417 Disease Relevance 0.39 Pain Relevance 0

General Comments

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