INT178204

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Context Info
Confidence 0.09
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.23
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Spa17) cytoplasm (Spa17)
Anatomy Link Frequency
Sperm 1
Spa17 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 9 5.00 Very Low Very Low Very Low
cytokine 8 5.00 Very Low Very Low Very Low
tolerance 4 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Multiple Myeloma 4 99.12 Very High Very High Very High
Ovarian Cancer 6 98.28 Very High Very High Very High
Cancer 202 97.84 Very High Very High Very High
Testicular Cancer 2 89.40 High High
Metastasis 4 74.36 Quite High
Genital Human Papilloma Virus 3 13.44 Low Low
Skin Cancer 16 5.00 Very Low Very Low Very Low
Immunization 8 5.00 Very Low Very Low Very Low
Targeted Disruption 8 5.00 Very Low Very Low Very Low
Death 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Sperm protein 17 (Sp17) could be an ideal target for the treatment of multiple myeloma and ovarian cancer, because it seems to have a very restricted distribution in healthy tissues and in vivo clinical safety could be deduced from the apparent lack of any pathological condition in men who develop anti-Sp17 antibodies after undergoing vasectomy.
Regulation (target) of Sp17 in Sperm associated with ovarian cancer and multiple myeloma
1) Confidence 0.09 Published 2004 Journal J Transl Med Section Body Doc Link PMC441417 Disease Relevance 1.23 Pain Relevance 0

General Comments

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