INT178286

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Context Info
Confidence 0.61
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 9
Total Number 9
Disease Relevance 3.86
Pain Relevance 0.50

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (Hps1) cytoplasmic membrane-bounded vesicle (Hps1)
Anatomy Link Frequency
Granulosa cells 1
reservoirs 1
Hps1 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 11 99.96 Very High Very High Very High
Inflammation 6 99.80 Very High Very High Very High
Pain 4 96.60 Very High Very High Very High
Hippocampus 12 83.44 Quite High
alcohol 5 65.24 Quite High
imagery 6 50.00 Quite Low
Central nervous system 3 33.80 Quite Low
Potency 9 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
isoflurane 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hantavirus Infection 87 100.00 Very High Very High Very High
INFLAMMATION 6 99.80 Very High Very High Very High
Infection 36 97.18 Very High Very High Very High
Pain 3 96.60 Very High Very High Very High
Blister 6 92.48 High High
Cancer 49 90.88 High High
Necrosis 6 88.88 High High
Disease 15 88.52 High High
Arenavirus Infection 30 81.84 Quite High
Targeted Disruption 32 52.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Sin Nombre virus is the only virus known to cause HPS in these 6 states.
Positive_regulation (cause) of HPS associated with hantavirus infection
1) Confidence 0.61 Published 2007 Journal Emerging Infectious Diseases Section Body Doc Link PMC2725987 Disease Relevance 0.51 Pain Relevance 0
Together, the high case-fatality ratio of HPS in North America, the lack of a vaccine against HPS, and the lack of a specific therapy for HPS should motivate persons to minimize their risk for infection while working in the field, classroom, or laboratory with rodents potentially infected with hantaviruses, especially those viruses known to cause HPS.
Positive_regulation (cause) of HPS associated with infection and hantavirus infection
2) Confidence 0.44 Published 2007 Journal Emerging Infectious Diseases Section Body Doc Link PMC2725987 Disease Relevance 0.86 Pain Relevance 0
Specific members of the subfamilies Neotominae and Sigmodontinae in the rodent family Cricetidae (11) are the principal hosts (reservoirs) of the hantaviruses known to cause HPS in North America and the 3 North American arenaviruses.
Positive_regulation (cause) of HPS in reservoirs associated with hantavirus infection
3) Confidence 0.41 Published 2007 Journal Emerging Infectious Diseases Section Body Doc Link PMC2725987 Disease Relevance 0.87 Pain Relevance 0
Grouping of HPs by predicted function
Positive_regulation (Grouping) of HPs
4) Confidence 0.19 Published 2004 Journal Proteome Sci Section Body Doc Link PMC446209 Disease Relevance 0 Pain Relevance 0.04
Also, for EP inductions were larger when measured ex vivo than when measured with IVIS (data not shown).
Positive_regulation (inductions) of EP
5) Confidence 0.08 Published 2004 Journal Environ Health Perspect Section Body Doc Link PMC1247619 Disease Relevance 0.05 Pain Relevance 0
In this time course, low levels of surface damage were observed, although a significant increase with EP alone was observed over plasmid injection alone at day 22.
Positive_regulation (increase) of EP
6) Confidence 0.06 Published 2008 Journal Genet Vaccines Ther Section Body Doc Link PMC2631522 Disease Relevance 0.50 Pain Relevance 0.09
Granulosa cells cultured in the absence of EP agonists produced approximately 1 × 10-19 mol cAMP/cell·hour, while cells cultured in the presence of PGE2 produced approximately 3 × 10-19 mol cAMP/cell·hour, indicating that contamination with about 10,000 cells/50 ?
Positive_regulation (absence) of EP in Granulosa cells associated with agonist
7) Confidence 0.06 Published 2010 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2988801 Disease Relevance 0 Pain Relevance 0.18
Electrodes of three different configurations can be used for EP pulse delivery during electrochemotherapy.
Positive_regulation (used) of EP
8) Confidence 0.05 Published 2008 Journal Med Biol Eng Comput Section Body Doc Link PMC2491703 Disease Relevance 0.56 Pain Relevance 0.10
Inflammation was also increased with EP alone at this time point.
Positive_regulation (increased) of EP associated with inflammation
9) Confidence 0.05 Published 2008 Journal Genet Vaccines Ther Section Body Doc Link PMC2631522 Disease Relevance 0.51 Pain Relevance 0.09

General Comments

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