INT178299

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Context Info
Confidence 0.63
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 0.82
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Myc) DNA binding (Myc) protein complex (Myc)
cytoplasm (Myc) pigmentation (Myc) chromosome organization (Myc)
Anatomy Link Frequency
hepatocytes 1
Myc (Mus musculus)
Pain Link Frequency Relevance Heat
Nerve growth factor 1 78.16 Quite High
Hippocampus 12 50.00 Quite Low
Central nervous system 5 5.00 Very Low Very Low Very Low
alcohol 4 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
medulla 2 5.00 Very Low Very Low Very Low
long-term potentiation 1 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 145 99.10 Very High Very High Very High
Neurodegenerative Disease 4 75.20 Quite High
Targeted Disruption 48 50.00 Quite Low
Down Syndrome 11 45.20 Quite Low
Hepatocellular Cancer 56 35.76 Quite Low
Liver Cancer 20 34.16 Quite Low
Malignant Neoplastic Disease 12 33.60 Quite Low
Severe Combined Immunodeficiency 10 29.28 Quite Low
Hyperplasia 32 24.88 Low Low
Apoptosis 52 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We obtained similar results by quantitative PCR analysis of mRNA expression of the human MYC transgene (Figure 3C).
Transcription (expression) of MYC
1) Confidence 0.63 Published 2004 Journal PLoS Biology Section Body Doc Link PMC519000 Disease Relevance 0.34 Pain Relevance 0
In tumors from embryos, neonatal, and adult mice, the levels of MYC transgene RNA increased an additional 10-fold over the levels observed in nonmalignant hepatocytes (Figure 3C).
Transcription (levels) of MYC in hepatocytes associated with cancer
2) Confidence 0.53 Published 2004 Journal PLoS Biology Section Body Doc Link PMC519000 Disease Relevance 0.34 Pain Relevance 0
LMW-PTP action is exerted during the G1 phase of the cell cycle and affects myc and fos gene transcription induced by PDGF-receptors activation [33].
Transcription (transcription) of myc
3) Confidence 0.30 Published 2004 Journal Proteome Sci Section Body Doc Link PMC446209 Disease Relevance 0.14 Pain Relevance 0.04
The endogenous mRNA expression of Oct3/4, Sox2, Klf4, c-Myc, p53, p21 and Tert in pGFs, mGFs and TTFs at passages 4 to 6 was determined by real-time RT-PCR analysis.
Transcription (expression) of Myc
4) Confidence 0.16 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2939066 Disease Relevance 0 Pain Relevance 0

General Comments

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