INT178328

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.50
First Reported 2004
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.20
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Pon1) extracellular region (Pon1)
Anatomy Link Frequency
erythrocyte 1
Pon1 (Mus musculus)
Pain Link Frequency Relevance Heat
psoriasis 63 96.36 Very High Very High Very High
rheumatoid arthritis 1 69.20 Quite High
Inflammation 16 39.28 Quite Low
Angina 9 5.00 Very Low Very Low Very Low
alcohol 3 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
drug abuse 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
methotrexate 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Psoriasis 106 96.36 Very High Very High Very High
Coronary Artery Disease 72 96.36 Very High Very High Very High
Disease 28 93.92 High High
Nicotine Addiction 4 85.04 High High
Diabetes Mellitus 10 82.24 Quite High
Atherosclerosis 20 77.48 Quite High
Rheumatoid Arthritis 2 69.36 Quite High
Systemic Lupus Erythematosus 2 68.28 Quite High
Renal Failure 1 66.88 Quite High
Myocardial Infarction 7 64.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Finally, it is possible that the PON1 Q192R polymorphism is not the true functional polymorphism for PON1 activity but is linkage disequilibrium with the functional variant.
Neg (not) Positive_regulation (polymorphism) of PON1
1) Confidence 0.50 Published 2004 Journal BMC Genet Section Body Doc Link PMC449704 Disease Relevance 0.70 Pain Relevance 0
The impaired antioxidant status is shown by decreased serum levels of erythrocyte SOD [51, 90] and GSH-Px activities [51, 90, 92, 93] of increased PON1 activity [54] and of increased [90] or decreased [51] serum CAT activity in patients with psoriasis.
Positive_regulation (increased) of PON1 in erythrocyte associated with psoriasis
2) Confidence 0.43 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2914266 Disease Relevance 1.50 Pain Relevance 0.22

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox