INT178332

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Context Info
Confidence 0.05
First Reported 2004
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 3.88
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (SUGT1) mitosis (SUGT1)
SUGT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
tolerance 5 42.40 Quite Low
Angina 11 5.00 Very Low Very Low Very Low
cytokine 5 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
alcohol 3 5.00 Very Low Very Low Very Low
drug abuse 2 5.00 Very Low Very Low Very Low
Inflammatory marker 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 176 100.00 Very High Very High Very High
Coronary Artery Disease 180 98.52 Very High Very High Very High
Obesity 56 89.36 High High
Atherosclerosis 11 72.48 Quite High
Disorder Of Lipid Metabolism 13 67.92 Quite High
Targeted Disruption 1 63.84 Quite High
Nicotine Addiction 4 48.64 Quite Low
Impaired Glucose Tolerance 5 43.76 Quite Low
Starvation 1 38.08 Quite Low
Body Weight 4 30.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Indeed, the protective role of Ala12 allele against T2D is considerably affected by dietary lipid levels.
Regulation (affected) of allele associated with diabetes mellitus
1) Confidence 0.05 Published 2009 Journal PPAR Research Section Body Doc Link PMC2669649 Disease Relevance 0.88 Pain Relevance 0
Thus, the variable assumes the value of 1 (reference group) in the absence of both diabetes and the variant S allele, the value of 2 in the presence of both diabetes and the S allele, 3 in the absence of diabetes and presence of the mutant R allele, and 4 in the presence of both diabetes and the R allele.
Regulation (value) of allele associated with diabetes mellitus
2) Confidence 0.01 Published 2007 Journal BMC Med Genet Section Body Doc Link PMC1933415 Disease Relevance 1.13 Pain Relevance 0
Thus, the variable assumes the value of 1 (reference group) in the absence of both diabetes and the variant S allele, the value of 2 in the presence of both diabetes and the S allele, 3 in the absence of diabetes and presence of the mutant R allele, and 4 in the presence of both diabetes and the R allele.
Regulation (value) of allele associated with diabetes mellitus
3) Confidence 0.01 Published 2007 Journal BMC Med Genet Section Body Doc Link PMC1933415 Disease Relevance 1.01 Pain Relevance 0
If the Q192R polymorphism has pleiotropic effects (the potential for polymorphisms to have more than one specific phenotypic effect) with some, as yet unknown, phenotypic effect of the R allele that results in a decreased risk of CHD then the overall effect of this polymorphism could be null, but the antioxidant properties of PON1 activity could still be an important determinant of risk.
Regulation (effect) of R allele associated with coronary artery disease
4) Confidence 0.00 Published 2004 Journal BMC Genet Section Body Doc Link PMC449704 Disease Relevance 0.86 Pain Relevance 0

General Comments

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