INT178497

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Context Info
Confidence 0.19
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 3.65
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Angpt1) signal transduction (Angpt1) extracellular space (Angpt1)
extracellular region (Angpt1) plasma membrane (Angpt1)
Anatomy Link Frequency
corneas 4
colon 2
Angpt1 (Mus musculus)
Pain Link Frequency Relevance Heat
Somatostatin 2 91.84 High High
fibrosis 10 88.96 High High
interstitial cystitis 2 86.48 High High
Inflammation 6 53.96 Quite High
chemokine 4 53.96 Quite High
cytokine 6 36.00 Quite Low
metalloproteinase 13 5.00 Very Low Very Low Very Low
anesthesia 6 5.00 Very Low Very Low Very Low
ischemia 3 5.00 Very Low Very Low Very Low
Potency 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Colon Cancer 6 100.00 Very High Very High Very High
Lung Injury 1 99.88 Very High Very High Very High
Cancer 179 98.40 Very High Very High Very High
Injury 24 93.16 High High
Fibrosis 17 88.96 High High
Interstitial Cystitis 2 86.48 High High
Hypertension 1 86.48 High High
Corneal Neovascularization 74 86.08 High High
Vasculitis 3 85.36 High High
Pressure And Volume Under Development 1 84.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Increased expression of Ang-1 was noted in mice treated with the transfected MSCs and persisted for 14 days until sacrifice [45].
Positive_regulation (Increased) of Gene_expression (expression) of Ang-1
1) Confidence 0.19 Published 2010 Journal Stem Cells International Section Body Doc Link PMC3022195 Disease Relevance 1.35 Pain Relevance 0.22
Recently, Stoeltzing et al liposomally transfected human colon cancer cells with an Ang-1 construct.
Positive_regulation (transfected) of Gene_expression (transfected) of Ang-1 in colon associated with colon cancer
2) Confidence 0.18 Published 2004 Journal J Transl Med Section Body Doc Link PMC455695 Disease Relevance 0.91 Pain Relevance 0.03
As previous studies have shown, overexpression of VEGF, bFGF, PDGF, nitric oxide synthases, angiopoietin, and angiopoietin 2 were detected in alkali-burned corneas as early as 3 days [1].
Positive_regulation (overexpression) of Gene_expression (overexpression) of angiopoietin in corneas
3) Confidence 0.04 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2913137 Disease Relevance 0.70 Pain Relevance 0.07
As previous studies have shown, overexpression of VEGF, bFGF, PDGF, nitric oxide synthases, angiopoietin, and angiopoietin 2 were detected in alkali-burned corneas as early as 3 days [1].
Positive_regulation (overexpression) of Gene_expression (overexpression) of angiopoietin in corneas
4) Confidence 0.03 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2913137 Disease Relevance 0.70 Pain Relevance 0.07

General Comments

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