INT178535

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Context Info
Confidence 0.19
First Reported 2004
Last Reported 2009
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 4
Disease Relevance 2.91
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (CSTB) nucleus (CSTB) intracellular (CSTB)
cytoplasm (CSTB)
CSTB (Homo sapiens)
Pain Link Frequency Relevance Heat
Bile 2 72.36 Quite High
corticosteroid 4 50.28 Quite High
fluoxetine 4 5.00 Very Low Very Low Very Low
diclofenac 2 5.00 Very Low Very Low Very Low
Analgesic 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adverse Drug Reaction 128 99.20 Very High Very High Very High
Breast Cancer 46 98.48 Very High Very High Very High
Carcinoma 16 98.36 Very High Very High Very High
Deafness 14 89.44 High High
Cancer 136 88.52 High High
Adenocarcinoma 2 83.76 Quite High
Rhabdomyolysis 8 80.72 Quite High
Gallstones 12 73.68 Quite High
Staphylococcus Infection 54 53.40 Quite High
Syndrome 52 52.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The objective of the current studies was to determine if PME gene expression levels have been altered in breast tumorigenesis.
Regulation (altered) of Spec (determine) Gene_expression (expression) of PME gene
1) Confidence 0.19 Published 2004 Journal BMC Cancer Section Body Doc Link PMC459223 Disease Relevance 0.51 Pain Relevance 0.03
The findings suggest that selective changes in specific PME expression levels could lead to local increases in carcinoma-promoting 5?
Regulation (changes) of Gene_expression (expression) of PME associated with carcinoma
2) Confidence 0.17 Published 2004 Journal BMC Cancer Section Body Doc Link PMC459223 Disease Relevance 0.66 Pain Relevance 0
Construction of the binary classification model using the CPI profile
Regulation (using) of Gene_expression (profile) of CPI
3) Confidence 0.04 Published 2009 Journal PLoS Computational Biology Section Body Doc Link PMC2704868 Disease Relevance 0.69 Pain Relevance 0
CPI profile of a drug reflects its interacting character towards multi-protein set
Regulation (reflects) of Gene_expression (profile) of CPI
4) Confidence 0.04 Published 2009 Journal PLoS Computational Biology Section Body Doc Link PMC2704868 Disease Relevance 1.04 Pain Relevance 0.04

General Comments

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