INT178547

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Context Info
Confidence 0.29
First Reported 2004
Last Reported 2010
Negated 1
Speculated 1
Reported most in Body
Documents 9
Total Number 10
Disease Relevance 6.53
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (CSTB) nucleus (CSTB) intracellular (CSTB)
cytoplasm (CSTB)
CSTB (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 35 97.08 Very High Very High Very High
Bile 7 72.36 Quite High
corticosteroid 4 50.28 Quite High
fluoxetine 14 5.00 Very Low Very Low Very Low
Inflammatory response 9 5.00 Very Low Very Low Very Low
diclofenac 7 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
Analgesic 2 5.00 Very Low Very Low Very Low
Inflammatory stimuli 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Mouth Disease 31 99.92 Very High Very High Very High
Syndrome 182 99.60 Very High Very High Very High
Adverse Drug Reaction 448 99.20 Very High Very High Very High
Staphylococcus Infection 189 98.96 Very High Very High Very High
Carcinoma 16 98.36 Very High Very High Very High
Breast Cancer 46 97.68 Very High Very High Very High
INFLAMMATION 46 97.08 Very High Very High Very High
Disease 5 96.56 Very High Very High Very High
Hypersensitivity 56 93.40 High High
Exanthema 14 92.72 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The objective of the current studies was to determine if PME gene expression levels have been altered in breast tumorigenesis.
Spec (determine) Gene_expression (expression) of PME gene
1) Confidence 0.29 Published 2004 Journal BMC Cancer Section Body Doc Link PMC459223 Disease Relevance 0.45 Pain Relevance 0.03
Cystatin B and Annexin A1 were found by Bostanci et al.(29) only in healthy volunteers and not in developing inflammatory disease.
Neg (not) Gene_expression (found) of Cystatin B associated with inflammation and disease
2) Confidence 0.26 Published 2010 Journal Journal of Proteome Research Section Body Doc Link PMC2950674 Disease Relevance 0.85 Pain Relevance 0.12
The findings suggest that selective changes in specific PME expression levels could lead to local increases in carcinoma-promoting 5?
Gene_expression (expression) of PME associated with carcinoma
3) Confidence 0.25 Published 2004 Journal BMC Cancer Section Body Doc Link PMC459223 Disease Relevance 0.66 Pain Relevance 0
Construction of the test CPI
Gene_expression (Construction) of CPI
4) Confidence 0.06 Published 2009 Journal PLoS Computational Biology Section Body Doc Link PMC2704868 Disease Relevance 0 Pain Relevance 0
The basic hypothesis of the CPI
Gene_expression (hypothesis) of CPI
5) Confidence 0.06 Published 2009 Journal PLoS Computational Biology Section Body Doc Link PMC2704868 Disease Relevance 0.25 Pain Relevance 0
Drugs sharing the same SADR outcome were also found to possess similarities in their CPI profiles towards this 845 protein set.
Gene_expression (profiles) of CPI associated with adverse drug reaction
6) Confidence 0.06 Published 2009 Journal PLoS Computational Biology Section Abstract Doc Link PMC2704868 Disease Relevance 1.12 Pain Relevance 0
Availability and limitations of the CPI related techniques
Gene_expression (techniques) of CPI
7) Confidence 0.06 Published 2009 Journal PLoS Computational Biology Section Body Doc Link PMC2704868 Disease Relevance 0.38 Pain Relevance 0
CPI profile of a drug reflects its interacting character towards multi-protein set
Gene_expression (profile) of CPI
8) Confidence 0.06 Published 2009 Journal PLoS Computational Biology Section Body Doc Link PMC2704868 Disease Relevance 1.03 Pain Relevance 0.04
Construction of the binary classification model using the CPI profile
Gene_expression (profile) of CPI
9) Confidence 0.06 Published 2009 Journal PLoS Computational Biology Section Body Doc Link PMC2704868 Disease Relevance 0.64 Pain Relevance 0
Identification of candidate genes of serious cutaneous reactions through mining the CPI
Gene_expression (mining) of CPI
10) Confidence 0.06 Published 2009 Journal PLoS Computational Biology Section Body Doc Link PMC2704868 Disease Relevance 1.13 Pain Relevance 0

General Comments

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