INT17855

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Context Info
Confidence 0.34
First Reported 1988
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 6
Disease Relevance 1.42
Pain Relevance 0.80

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (G6pd) oxidoreductase activity (G6pd) nucleus (G6pd)
carbohydrate metabolic process (G6pd) cytoplasm (G6pd)
Anatomy Link Frequency
dorsal 1
lateral 1
reticulocyte 1
G6pd (Rattus norvegicus)
Pain Link Frequency Relevance Heat
IPN 8 98.96 Very High Very High Very High
Pain 3 98.48 Very High Very High Very High
Neuropeptide 2 89.08 High High
Analgesic 2 66.00 Quite High
Disease Link Frequency Relevance Heat
Pain 3 98.48 Very High Very High Very High
Sickle Cell Anemia 6 98.36 Very High Very High Very High
Hemolysis 2 94.28 High High
Anaemia 3 93.72 High High
Malaria 2 88.48 High High
Thalassemia 3 86.24 High High
Favism 1 81.32 Quite High
Infection 1 67.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Histochemical staining for glucose-6-phosphate dehydrogenase (G6PDH) is most intense in the dorsal-medial subnucleus, followed in order of diminishing intensity by the rostral, rostral-lateral, dorsal-lateral, lateral, central, intermediate, and apical subnuclei.
glucose-6-phosphate dehydrogenase Binding (staining) of in dorsal
1) Confidence 0.34 Published 1988 Journal Brain Res. Bull. Section Abstract Doc Link 3365561 Disease Relevance 0 Pain Relevance 0.29
This cross-sectional study hypothesizes that if the fava bean and G6PD deficiency interact in the Thai population, they should cause a significant difference in hematocrit level.
G6PD Binding (interact) of
2) Confidence 0.33 Published 1991 Journal Southeast Asian J. Trop. Med. Public Health Section Abstract Doc Link 1948276 Disease Relevance 0.48 Pain Relevance 0.07
In conclusion, G6PD(202A,376G) may be associated with lower haemoglobin concentration in sickle cell anaemia by a mechanism other than increased haemolysis.
G6PD Binding (associated) of associated with sickle cell anemia
3) Confidence 0.13 Published 2010 Journal Br. J. Haematol. Section Abstract Doc Link 20507315 Disease Relevance 0.38 Pain Relevance 0.10
Association of G6PD with lower haemoglobin concentration but not increased haemolysis in patients with sickle cell anaemia.
G6PD Binding (Association) of associated with sickle cell anemia
4) Confidence 0.13 Published 2010 Journal Br. J. Haematol. Section Title Doc Link 20507315 Disease Relevance 0.28 Pain Relevance 0
Histochemical staining for glucose-6-phosphate dehydrogenase (G6PDH) is most intense in the dorsal-medial subnucleus, followed in order of diminishing intensity by the rostral, rostral-lateral, dorsal-lateral, lateral, central, intermediate, and apical subnuclei.
glucose-6-phosphate dehydrogenase Binding (staining) of in lateral
5) Confidence 0.12 Published 1988 Journal Brain Res. Bull. Section Abstract Doc Link 3365561 Disease Relevance 0 Pain Relevance 0.29
G6PD(202A,376G) was associated with a 10 g/l decrease in haemoglobin concentration (P = 0.008) but not with increased haemolysis as measured by lactate dehydrogenase, bilirubin, aspartate-aminotransferase, reticulocyte count or a haemolytic component derived from these markers (P > 0.09).
G6PD Binding (associated) of in reticulocyte
6) Confidence 0.11 Published 2010 Journal Br. J. Haematol. Section Abstract Doc Link 20507315 Disease Relevance 0.29 Pain Relevance 0.05

General Comments

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